Words similar to fold-changes
Example sentences for: fold-changes
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For each of the four metrics, computed fold-changes between the modulated condition and the baseline (considering only messages called Present) were compared to the true fold-changes.
1 μg) can be used with our simplified amplification protocol to detect differential gene expression, (3) biological variation is larger than technical variation, (4) very low-level signals are prone to false positives and to less reliable fold-changes, false positives can be reduced by filtering out probe sets not reliably detected before statistical comparisons, and (5) using 4 independent biological samples is much better than using 3 samples in allowing detection of consistent changes and reducing false positives.
The largest fold-changes in highly expressed genes can usually be trusted.
It is, however, possible to achieve very small p -values for tiny fold-changes, as small as 1.1.
Those probe sets with a unadjusted significance of P < 0.05 (blue), P < 0.01 (green) or P < 0.001 (red) are indicated on the scatter plots in Figures 1Cand 1D, while the distribution of significant differences at different fold-changes is illustrated in the table in Figure 1E.