Words similar to fold-change
Example sentences for: fold-change
How can you use “fold-change” in a sentence? Here are some example sentences to help you improve your vocabulary:
Typically, an arbitrary value for expression ratios (or fold-change values) is chosen to define significant differences in gene expression between conditions.
For comparison, the expression data were also filtered using an ad hoc fold-change method.
The inverse also holds true, where highly expressed genes, having less error in their measured levels, may not meet an arbitrary fold-change cut-off of 2.0 even when they are truly differentially expressed [ 12 ] . Therefore, selecting differentially regulated genes based only on a single fold change across the entire range of experimental data preferentially selects lowly expressed genes [ 8 ] . This commonly used approach does not accommodate for background noise, variability, non-specific binding, or low copy numbers- characteristics typical of microarray data which may not be homogeneously distributed.
We then assigned those Connections Map proteins with a 1.5 or greater fold-change to functional groups as described above.
Absolute changes in expression at different sample sizes are presented as minimum detectable fold-changes in expression using the following formula: Minimum detectable fold-change = (average expression value of the six upregulated genes in control cultures + size of the detectable difference)/average expression value of the six upregulated genes in control cultures.