Example sentences for: fold-change

How can you use “fold-change” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • During preparation of this manuscript, an expression profiling study of seven renal neoplasms (four CC, 2 oncocytomas, and one Chr) was reported [ 24 ] . This study employed a different platform (Incyte glass slide cDNA microarray) and hybridization method (competitive tumor/normal binding), and used related but not identical gene selection criteria (two fold-change in expression versus normal kidney in at least two of the seven tumors).

  • Fold-change values were calculated as the ratio of gene expression values between each tumor-normal sample pair from the same patient, with the normal sample values used as the baseline.

  • These low-intensity spots are those most aberrant in fold-change and are those for which the magnitude is adjusted most by the model of Newton et al . [ 36].

  • For comparison, the expression data were also filtered using an ad hoc fold-change method.

  • For genes selected as either increased or decreased in a particular RCCa subtype both samples had to show concordance in their fold-change and difference call, and both samples from the other subtype had to have a difference call of no change (NC) or a call that was opposite to that of the first subtype.


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