Words similar to fold-change
Example sentences for: fold-change
How can you use “fold-change” in a sentence? Here are some example sentences to help you improve your vocabulary:
1) that have a 1.5 or greater fold-change to functional groups ( i.e., cell cycle, apoptosis, signal transduction, etc.) which have biological significance.
However, because the 'correct' fold-change limit typically shifts with decreasing intensity of expression, a fixed fold-change line is inadequate in the range of expression levels where most genes actually lie.
The inverse also holds true, where highly expressed genes, having less error in their measured levels, may not meet an arbitrary fold-change cut-off of 2.0 even when they are truly differentially expressed [ 12 ] . Therefore, selecting differentially regulated genes based only on a single fold change across the entire range of experimental data preferentially selects lowly expressed genes [ 8 ] . This commonly used approach does not accommodate for background noise, variability, non-specific binding, or low copy numbers- characteristics typical of microarray data which may not be homogeneously distributed.
We then assigned those Connections Map proteins with a 1.5 or greater fold-change to functional groups as described above.
To increase sensitivity, the fold-change threshold was decreased to 1.4 and the scaled signal change cut-off to 25.