Example sentences for: fold-change

How can you use “fold-change” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To select genes for further analysis from the pilot data set, a two fold-change threshold was used in combination with the Affymetrix difference call of either increase (I), marginal increase (MI), decrease (D) and marginal decrease (MD).

  • Reduction of total sample size from 16 to 12 modestly increased the minimum detectable fold-change from 3.0 to 3.8.

  • Absolute changes in expression at different sample sizes are presented as minimum detectable fold-changes in expression using the following formula: Minimum detectable fold-change = (average expression value of the six upregulated genes in control cultures + size of the detectable difference)/average expression value of the six upregulated genes in control cultures.

  • We note that although it is advantageous to work in a log scale for the fold-change interpretation, it means that those genes with tag count of zero in either library are deleted from the picture.

  • For genes selected as either increased or decreased in a particular RCCa subtype both samples had to show concordance in their fold-change and difference call, and both samples from the other subtype had to have a difference call of no change (NC) or a call that was opposite to that of the first subtype.


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