Example sentences for: fold-change

How can you use “fold-change” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Fold-change values were calculated as the ratio of gene expression values between each tumor-normal sample pair from the same patient, with the normal sample values used as the baseline.

  • To increase sensitivity, the fold-change threshold was decreased to 1.4 and the scaled signal change cut-off to 25.

  • To select genes that were changed between CC and Chr in our pilot data set we used an arbitrary cutoff of 2 fold-change units in combination with the Affymetrix difference call (see Methods).

  • A lower false-positive rate was achieved, at the expense of sensitivity, by increasing the average difference (signal) change requirement from 50 to 200 and maintaining the qualitative criteria and the fold-change threshold at 1.8.

  • The expression results for the genes JUN ( c-jun ) and VHL ( von Hippel-Lindau ) did not match the literature [ 18 19 ] . Nor did the result for KRT7 ( cytokeratin 7 ), which has been shown to be overexpressed in Chr [ 20 ] . Instead we found KRT7 to be strongly repressed in CC (fold-change = -5.


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