Example sentences for: folates

How can you use “folates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [ 35 ] Additional in vitro studies suggest cells may need prolonged exposure to reduced folates in order to obtain maximum inhibition of TS by FdUMP.

  • SAHH may have significant impact on the conceptuses ability to use folates during this transitional stage of development.

  • Folates have long been known to be an essential requirement for developing embryos, predominately during neurulation [ 21 ] . Vallet and coworkers [ 22 ] have previously shown the increase in maternal folate binding protein activity occurs in the uterine lumen of cyclic and pregnant gilts between days 10-12 post-estrus.

  • There is a high degree of amino acid similarity among folate transporters and the thiamine transporter of the plasma membrane [ 7 8 9 10 ] . Recently, it was found that in murine cells there can be a substantial efflux of ThDP mediated by the reduced folate carrier protein [ 22 ] . GlyB cells are a Chinese hamster ovary cell line derivative that are deficient in the transport of folates into mitochondria, and the responsible mitochondrial transporter has recently been identified and its gene cloned [ 23 ] . We wondered if the mitochondrial folate transporter was responsible for uptake of ThDP into mitochondria, making analogies to the ability of the plasma membrane folate transporter being able to transport ThDP.


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