Words similar to exogenous
Example sentences for: exogenous
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It should be noted that the fibroblast cells lines we used remain fully viable after detachment and transfer to suspension culture [ 31 43 ] . This is in contrast to most epithelial cells which undergo anoikis, i.e., apoptotic cell death after the disruption of cell-matrix interactions [ 45 ] . It is of interest that some anchorage-independent tumor cells, most of which are of epitheloid origin, become susceptible to anoikis after the introduction of exogenous PTEN [ 23 34 35 36 ] . These observations are in line with the established ability of PTEN to down-regulate the phosphatidylinositol 3-kinase (PI3-K)/PKB survival pathway [ 11 46 ] . The absence of anoikis in our two cell lines may reflect inherent cell type specific differences, i.e., the superior ability of fibroblasts to survive under suspension culture conditions.
RT-PCR analysis confirmed that the exogenous pBluII RNA was equally distributed between the cytosolic and cytoskeleton-associated fractions.
DNA synthesis on exogenous RNA templates
Again, no specific DHBV RNAseH cleavage was observed (data not shown), indicating that using different region of RNA from the DHBV genome did not affect the observation that the DHBV RNAseH could not engage an exogenous substrate.
Fibronectin contains three types of homology sequences, I-III; type I sequences bind heparin, Staphylococcus aureus, fibrin, and cell surfaces, type II sequences bind collagen and gelatin, and type III sequences bind DNA, cell surfaces, heparin, and fibulin-1 [ 40 43 ] . Fibulin-1 interacts with fibronectin through a heparin-binding region in type III 13 repeat; the binding of fibulin-1 to this site is independent of the binding of heparin as addition of exogenous heparin does not inhibit fibulin-1 binding to fibronectin [ 40 ] . The fibronectin-binding site in fibulin-1 is located in EGF-like modules 5 and 6 [ 44 ] ; the binding of fibulin-1 to fibronectin is a heterotypic interaction in which an EGF-like module binds to a non EGF-like domain (the type III 13 fibronectin repeat) [ 40 ] .
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