Example sentences for: exogenous

How can you use “exogenous” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Though BDM does not inhibit nm-myosinII, in permeabilized yeast ( S. cerviseae ) BDM has been shown to decrease incorporation of exogenous actin into the cytoskeleton [ 20 ] . This process of actin incorporation requires proteins involved in actin filament formation and proteins that may localize a nucleation complex [ 20 21 ] . To determine if BDM has a similar effect on actin incorporation in mammalian cells, and if so an effect on actin nucleation, spreading Swiss3T3 cells were treated briefly with a media control or 15 mM BDM and then permeabilized with the detergent saponin in the presence of fluorescently labeled actin.

  • Finally, the retroviral genome is small, limiting the size of exogenous genes that can be packaged.

  • In addition, exogenous catecholamines, used to maintain arterial pressure during septic shock, interfere with hypoxic pulmonary vasoconstriction: vasodilators like isoproterenol or dobutamine tend to inhibit hypoxic pulmonary vasoconstriction whereas vasoconstrictors like dopamine, epinephrine or norepinephrine tend to reinforce hypoxic pulmonary vasoconstriction.

  • These results are consistent with data reported for palatal fibroblasts [ 43 ] , but contrast with observations on corneal fibroblasts [ 45 ] . In the absence of exogenous TGFβ1, keloid fibroblasts accumulated the most α-SMA - Fig.

  • In the lens, alpha-crystallin also associates with type III intermediate filament proteins and the beaded filament proteins CP49 and CP115, and correct beaded filament assembly has been shown depend on the presence of alpha-crystallin [ 16 ] . Beaded filament mRNA levels are greatly increased in differentiating lens epithelium and have been suggested as a pan-specific marker for lens fiber development [ 17 ] . Alpha-crystallin has also been shown to interact directly with DNA [ 18 ] . In transfected CHO cells, alphaB has also been shown to ectopically localize to interphase nuclei, suggesting a role for this protein in the nucleus [ 19 ] . A nuclear role for alphaB in the lens was supported by the findings that a subset of lens epithelial cells derived from alphaB knockout mice demonstrated hyperproliferation and genomic instability [ 20 ] . In addition, the administration of exogenous alpha-crystallin to primary bovine lens epithelial cell cultures resulted in the formation of lentoid bodies, consistent with a role for these proteins in lens differentiation [ 21 ] . These findings indicate that alpha-crystallin may have a multitude of in vivo functions.


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