Words similar to exoenzyme

Example sentences for: exoenzyme

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C3 exoenzyme was purified as previously described [ 25 ] . Anti-β1 integrin mAb 33B6 and anti α4β1 integrin mAb 19H8 were generated in this laboratory and have been previously described [ 27 28 ] . Rabbit polyclonal anti-Cdc42, -Rac1, -Rac2, -RhoA, and mouse monoclonal anti-Ras, were purchased from Santa Cruz Biotechnology (Santa Cruz, CA).
Given the morphologic similarity between neurite outgrowth of N1E-115 cells and the aberrant pseudopodial extension of HPB-ALL when RhoA is inhibited with C3 exoenzyme, it will be interesting to determine if other GTPases such as Rac or Cdc42 are activated to promote this phenotype after C3 treatment of HPB-ALL cells.
Inactivation of Rho by electroporation of C3 exoenzyme did not seem to cause a large overall redistribution of RhoA in spread HPB-ALL.
Previous reports have demonstrated that ADP-ribosylation of B-lymphoid cell lines by C3 treatment inhibits phorbol ester induced cellular homotypic aggregation [ 18 ] . Also, phorbol ester and chemoattractant (IL-8 and fMLP) induced pre-B lymphoblastoid adhesion to VCAM-1 and neutrophil adhesion to fibrinogen was abrogated in a dose-dependent manner by C3 exoenzyme [ 36 ] . This may indicate that in cells of hematopoietic lineages, the induction of an increased adhesive state may be susceptible to regulation by Rho proteins.
Immunolocalization of the GTPase RhoA was performed to determine if inactivation by C3 exoenzyme caused spatial redistribution of RhoA in HPB-ALL.