Words similar to exogenously
Example sentences for: exogenously
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IL-6 given exogenously, since LNCaP cells do not produce IL-6, resulted in increased growth of the cells concomitant with activation of STAT3 [ 36 ] . LNCaP cells transfected with a plasmid conferring constitutive IL-6 expression demonstrated increased growth, relative to untransfected or sham-transfected cells [ 36 ] . However, other investigators have observed that IL-6 treatment of LNCaP cells reulted in terminal differentiation and inhibition of growth, associated with STAT3 activation [ 17 37 38 ] . The molecular basis for the apparent contradiction is unknown at this time.
DHBV RNAseH activity could be detected on RNA:DNA heteroduplexes synthesized within DHBV core particles in the process of viral reverse transcription, but no RNAseH activity could be detected exogenously provided RNA:DNA heteroduplexes.
Although such reports of increased vessel growth and functional improvement in response to exogenously administered angiogenic factors are encouraging, it is essential to note that animal models such as the ischemic hind limb model have definite limitations.
In addition, subsequent studies examining the roles of BMP, FGF's and Shh have also utilized Affigel Blue beads to exogenously introduce various protein components [ 24 25 ] . The results of these studies have been consistent with the known temporal and spatial distributions of these proteins.
Cholesterol oxides given exogenously can be cleared from plasma rapidly and be widely redistributed in different parts of the body [ 41 ] . Cholesterol oxides and authentic cholesterol are transported within the cell by a similar mechanism, but the transport is more efficient for cholesterol oxides [ 42 ] . High levels of cholesterol oxides have been observed in hypercholesterolemic animals.