Words similar to exonuclease
Example sentences for: exonuclease
How can you use “exonuclease” in a sentence? Here are some example sentences to help you improve your vocabulary:
The replicative polymerase of herpes simplex virus (HSV) is comprised of catalytic (Pol) and processivity subunits (UL42) [ 9 11 ] . HSV Pol is responsible, in concert with other viral proteins, for regulating the fidelity of DNA replication by selecting the correct nucleotides for incorporation and by proofreading or editing mispaired nucleotides [ 20 ] . The Pol subunit contains intrinsic 3'-5' exonuclease activity [ 14 15 16 ] and the N-terminal region of the polypeptide encoding this function is highly conserved in other polymerases, containing three segments referred to as Exo motifs [ 3 26 ] .
Genes for RecT/Redβ superfamily proteins are associated with genes encoding a λ-type exonuclease (LE) of the type II restriction enzyme fold, RecE, which also might be a divergent member of this fold, and a nuclease of the Endonuclease VII (EndoVII) fold [ 7 34 ] (Fig.
We have chosen to illustrate this approach using the multifunctional family of DNA repair proteins, the apurinic/apyrimidinic endonucleases (APEs), which have a clearly defined bacterial ancestor, E. coli exonuclease III (ExoIII), and are distantly related to several enzymes with varying substrate specificity.
After amplification, reactions were incubated at 37°C for 15 min with 0.5 Uμl -1exonuclease I (USB) and 0.5 Uμl -1shrimp alkaline phosphatase (Amersham Life Sciences).
As in the previous scenario, exonuclease erodes the end and pauses, telomerase returns and caps the ends it finds, and the observed spectrum of TASs is generated.
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