Words similar to exonuclease
Example sentences for: exonuclease
How can you use “exonuclease” in a sentence? Here are some example sentences to help you improve your vocabulary:
We have chosen to illustrate this approach using the multifunctional family of DNA repair proteins, the apurinic/apyrimidinic endonucleases (APEs), which have a clearly defined bacterial ancestor, E. coli exonuclease III (ExoIII), and are distantly related to several enzymes with varying substrate specificity.
The exact nucleotide positions where telomere repeats are added have been examined in several ciliates (reviewed by [ 23 53 ] ). Cloned chromosome ends from 81 MAC family indicated heterogeneity of TAS placement, which we attributed to exonuclease erosion of the broken ends prior to telomerase action [ 27 ] . Analogous multi-TAS regions have been described in Tetrahymena ( [ 49 ] ; E. Hamilton and E. Orias, pers.
Of the four protein areas that bind to the DNA 3' of the abasic site, mutating F266 (molego 10) or W280 (middle of molego 11) decreases APE activity [ 33 ] . The F266 mutation is particularly interesting, as the mutants at this position had reduced substrate specificity and enhanced 3'-exonuclease activity.
APEs also have RNase H, 3'-exonuclease, and 3'-phosphodiester activities that are particularly high in the bacterial members of the family [ 26 13 ] .
We purified the genomic amplicons with exonuclease and shrimp alkaline phosphatase (United States Biochemical) and sequenced them directly with primers E41S, E43S, E44AS and E47AS [ 15 ] .
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