Example sentences for: estrogenic

How can you use “estrogenic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Phenol red in tissue culture media is a weak estrogen, sufficient to stimulate the proliferation of ERα+ MCF-7 human breast carcinoma cells [ 36 ] . We report a similar estrogenic effect of PhR+ media on trophoblast differentiation and syncytium formation in cultures from normal placentae, but not from abnormal ones.

  • BRCA1 levels appear to affect the ability of cells to arrest growth or die in the absence of estrogenic growth-inducing conditions.

  • Future studies that control for estrogenic effects of ovarian activation, food availability, and body growth during the relatively protracted period of pheromonal induction of first estrus offer promise for extending our understanding of the role of social and environmental signals on body growth and sexual maturation.

  • Hence, trophoblast cells from abnormal placentae are also capable of differentiating in response to estrogenic stimuli, but the level of estrogens must be higher.

  • Trophoblast cells are usually separated and grown in media containing phenol red (PhR) [ 35 ] . Phenol red is a weak estrogen with apparent biological effects, and the ERα binding affinity in Dulbecco's Modified Eagle's Medium (DMEM) is equivalent to levels of E2 as high as 0.45 nM [ 36 ] . Although relatively low when compared to the E2 levels in pregnancy, this estrogenic binding affinity of PhR is close to that of E2 during the preovulatory peak [ 4 5 ] . Therefore, we included studies with PhR+, PhR-/E2- and PhR-/E2+ media in order to determine the effect of estrogens on differentiation of cultured trophoblast cells (syncytium formation) derived from normal and abnormal placental types.


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