Words similar to estrogenic
Example sentences for: estrogenic
How can you use “estrogenic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Hence, trophoblast cells from abnormal placentae are also capable of differentiating in response to estrogenic stimuli, but the level of estrogens must be higher.
Evidence may in fact suggest, although there is some debate, that exposure of female rhesus monkeys to aroclor 1254 (a mixture of PCB congeners) leads to a reduction in the sex ratio of offspring, possibly contributed to by increased spontaneous abortion of male fetuses [ 28 29 30 ] . Preconception parental estrogen levels have also been hypothesized to affect the sex ratio of live births [ 22 ] , and given the estrogenic and anti-estrogenic actions of different PCB congeners [ 57 58 ] , this could be another mechanism by which parental exposure to PCBs alters the sex ratio.
One might speculate that in cultures derived from normal placentae, the weak estrogenic effect of PhR is sufficient to stimulate trophoblast/mesenchymal cell interactions in vitro resulting in a local production of estrogens.
Trophoblast cells are usually separated and grown in media containing phenol red (PhR) [ 35 ] . Phenol red is a weak estrogen with apparent biological effects, and the ERα binding affinity in Dulbecco's Modified Eagle's Medium (DMEM) is equivalent to levels of E2 as high as 0.45 nM [ 36 ] . Although relatively low when compared to the E2 levels in pregnancy, this estrogenic binding affinity of PhR is close to that of E2 during the preovulatory peak [ 4 5 ] . Therefore, we included studies with PhR+, PhR-/E2- and PhR-/E2+ media in order to determine the effect of estrogens on differentiation of cultured trophoblast cells (syncytium formation) derived from normal and abnormal placental types.
This could be interpreted as evidence that soy increases breast cancer risk as a result of its estrogenic effects [ 3].
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