Example sentences for: estrogens

How can you use “estrogens” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Our observations indicate that the cultures from normal and abnormal placentae contain similar trophoblast cells capable of differentiating in response to exogenous estrogens, but they may differ in the ability of accompanying mesenchymal cells to promote this process.

  • In this regard, endocrine disrupters are environmental chemicals that mimic or modulate the physiological effects of steroid hormones, especially that of estrogens [ 23 24 ] . Of all of the considered estrogenic endocrine disrupters examined thus far, phytoestrogens have been extensively studied [ 23 24 ] (however, little research has been conducted examining VSM in relationship to phytoestrogens).

  • Trophoblast cells are usually separated and grown in media containing phenol red (PhR) [ 35 ] . Phenol red is a weak estrogen with apparent biological effects, and the ERα binding affinity in Dulbecco's Modified Eagle's Medium (DMEM) is equivalent to levels of E2 as high as 0.45 nM [ 36 ] . Although relatively low when compared to the E2 levels in pregnancy, this estrogenic binding affinity of PhR is close to that of E2 during the preovulatory peak [ 4 5 ] . Therefore, we included studies with PhR+, PhR-/E2- and PhR-/E2+ media in order to determine the effect of estrogens on differentiation of cultured trophoblast cells (syncytium formation) derived from normal and abnormal placental types.

  • As described in the Introduction, ERα and ERβ must interact differentially with factors that modulate ER activity in the presence of estrogens.

  • In vitro studies also show that estrogens can protect against a number of neurotoxic compounds [ 23].


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