Words similar to estrogens
Example sentences for: estrogens
How can you use “estrogens” in a sentence? Here are some example sentences to help you improve your vocabulary:
Although it was hypothesized that the polymorphism (A2 allele) could result in an additional Sp1 binding site with enhanced promoter activity and an increased rate of transcription [ 1 ] , this was not found in experimental studies [ 20 21 ] . Nonetheless, two studies found that both premenopausal and post-menopausal women with the variant A2 allele had higher levels of circulating estrogens than those with common alleles, indicating that the polymorphism may be in linkage disequilibrium with another functional polymorphism or that it may affect hormone levels through some other mechanism [ 4 22 ] .
Recently, much attention has been given to the neuroprotective properties of estrogens for both chronic neurodegenerative diseases and acute insults such as stroke.
Physical dependence, evidenced by the development of a withdrawal syndrome when a medication is suddenly withdrawn, is not evidence of addition [ 30 ] . Similar outcomes occur in the presence of exogenous hormones and other medications that act through cellular receptors (eg, estrogens, beta-blockers, alpha-2 agonists, caffeine, etc.).
Estrogen receptors have been identified in cultured fibroblasts of various origins and vascular smooth muscle cells [ 51 52 53 ] . Estrogens enhance proliferation of fibroblasts and inhibit vascular smooth muscle migration [ 54 55 ] . Binding of estrogens to fibroblasts also stimulates fibroblast interaction with epithelial cells with subsequent acceleration of maturation of epithelial cells [ 56 ] .
Yet, elevated maternal mid-trimester chorionic gonadotropin is associated with fetal cerebral blood flow redistribution and adverse perinatal outcome [ 63 ] . In addition, estrogens, which are known to cause a diminution of high LH levels in postmenopausal women, have been reported to be effective in the prevention and treatment of Alzheimer's disease [ 72 73 74 ] . Microglia belong among cells of the mononuclear phagocyte system [ 75 ] . Since CG increases secretion of a variety of cytokines by monocytes, and induces their inflammatory reaction and phagocytic activity [ 76 77 78 79 ] , high LH levels in aging individuals may also activate resident macrophages in the central nervous system and contribute to the development of Alzheimer's disease and other inflammation-mediated neurodegenerative diseases.
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