Words similar to estrogen
Example sentences for: estrogen
How can you use “estrogen” in a sentence? Here are some example sentences to help you improve your vocabulary:
The second set of analyses (fully adjusted) were adjusted for all covariates and potential confounders: age, sex, race, poverty to income ratio, body mass index, prevalent cardiovascular disease, prevalent diabetes, prevalent chronic inflammatory condition, current acute illness, and use of alcohol, non-steroidal anti-inflammatory medication, aspirin, and estrogen replacement.
Androgen exerts its biologic effects by binding to and activation of androgen receptor (AR) that trans-activates target genes through androgen responsive element (ARE) in the promoter of target genes [ 15 ] . In human breast cancer cells the effectiveness of retinoids in cell growth suppression was dictated by the presence of RAR [ 16 ] . Estrogen regulation of the expression of RAR α was mediated by interactions between estrogen receptor (ER) and estrogen responsive element (ERE) in the promoter of RAR α gene [ 17 ] . Because the DNA binding domains of steroid receptors including AR and ER are highly homologous, we postulated that similar mechanisms might also mediate the effect of androgen on RAR genes in prostate cells.
PERC PGC-1 related estrogen receptor coactivator
Human estrogen receptor alpha (hERα) is detected in 50-85% of all breast tumors [ 6 ] , and is utilized as a prognostic marker to identify patients who may have a favorable response to hormonal or endocrine manipulations.
Positive correlations have been seen with coronary heart disease, adult-onset diabetes mellitus and stroke [ 7 ] . However, the result with breast cancer has been inconsistent [ 8 ] . Abdominal obesity may be related to breast cancer through aberrant insulin signaling leading to increased endogenous androgen and estrogen levels [ 9 ] .
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