Example sentences for: estrogen

How can you use “estrogen” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • mRNA for estrogen receptor-α but not estrogen receptor-β could be detected in these cultures (Figure 3).

  • Androgen exerts its biologic effects by binding to and activation of androgen receptor (AR) that trans-activates target genes through androgen responsive element (ARE) in the promoter of target genes [ 15 ] . In human breast cancer cells the effectiveness of retinoids in cell growth suppression was dictated by the presence of RAR [ 16 ] . Estrogen regulation of the expression of RAR α was mediated by interactions between estrogen receptor (ER) and estrogen responsive element (ERE) in the promoter of RAR α gene [ 17 ] . Because the DNA binding domains of steroid receptors including AR and ER are highly homologous, we postulated that similar mechanisms might also mediate the effect of androgen on RAR genes in prostate cells.

  • Circadian rhythms in postpartum women are likely to suffer disturbances secondary to significant changes in estrogen and progesterone, which have been shown to advance and delay rhythms, respectively [ 30 ] , and it is plausible that bright light can help alleviate this.

  • Antisera against PLCγ2, ERK1, ERK2 and the hormone-binding domain of the estrogen receptor (ER) were from Santa Cruz Biotechnology (Santa Cruz, CA), and anti-active JNK antiserum was from Promega (Madison, WI).

  • For these reasons, we assessed the combined effects of HIV proteins and drugs of abuse, methamphetamine and cocaine on neuronal function and determined to what extent estrogen may protect against these neurotoxic substances.


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