Words similar to ep
Example sentences for: ep
How can you use “ep” in a sentence? Here are some example sentences to help you improve your vocabulary:
The rabbit EP 2 gene contains a 1,083 bp open reading frame coding for a 361 amino acid polypeptide, with a calculated molecular weight of 39,919 Daltons.
2 receptor mRNA expression was detected in the kidney and this was more pronounced in the renal cortex than in the medulla, no specific regions of EP 2 receptor mRNA expression could be detected in rabbit kidney by in situ hybridization [ 19 ] . Nonetheless, low levels of EP 2 receptor mRNA expression were detected by RT-PCR or RNase protection assay in nephron segments within the kidney including preglomerular vasculature, glomeruli, thin limbs of Henle's loop and collecting ducts.
This mRNA expression pattern is similar to that of the EP 2 in the mouse [ 5 21 ] . PGE 2 has been reported to stimulate cAMP formation in many tissues, including intestine, microdissected renal tubule segments, and uterus via butaprost sensitive and insensitive receptors [ 14 26 27 28 29 ] . The mRNA expression results are consistent with these functional studies and suggest that the EP 2 receptor plays important roles in mediating PGE2 stimulated cAMP generation in these tissues [ 14 21 26 27 28 29 30 31 32 33 ] .
Signal transduction properties of the EP 2receptor
With this information, cDNA sequence for all four rabbit EP receptors is now available [ 22 23 24 ] . Several similarities between the rabbit and mouse EP 2 receptors exist [ 5 21 ] . The rabbit EP 2 genomic clone contains an intron with consensus splice donor and acceptor sites near the end of transmembrane domain (TM) VI.
Loading...