Words similar to eosinophils
Example sentences for: eosinophils
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Characteristic features of atopic asthma are circulating specific IgE antibodies, positive skin tests to common allergens, and infiltration of the bronchial mucosa with eosinophils and Th2 cells.
Neutrophils, eosinophils and basophils are at concentration ranges of 1800-7000/μl, 0-300/μl, and 0-100/μl, respectively, in normal adults [ 18 ] . Accordingly, the total cells yielded from these preparations are typically 3 × 10 7, 2 × 10 6, and 6 × 10 5leukocytes per preparation of neutrophils, eosinophils, or basophils, respectively.
The CXC chemokines such as IL-8 were originally identified as potent activators and chemoattractants for neutrophils, whereas the CC chemokines such as MCP-1 and RANTES mostly attract monocytes and eosinophils respectively [ 10 ] . Chemokines are secreted in a stimulus-and cell type-specific manner [ 11 12 13 14 15 16 17 ] and are regulated primarily at the level of gene transcription [ 18 19 20 21 22 23 24 ] . The transcriptional promoters of IL-8, RANTES and MCP-1 contain binding sites for the redox-responsive transcription factor NF-κB, which has been shown to be important for their regulation by viral infections and cytokines [ 18 20 23 25 26 27 28 29 30 31 32 33 34 ] .
In the past, it has not been feasible to study cell populations that were represented at less than 2% of peripheral blood leukocytes such as basophils, eosinophils, or some lymphocyte subsets.
However, density gradient separation of PBMC almost totally compensated for these shifts by eliminating polymorphonuclear cells, eosinophils and basophils (Figure 1c), and leaving a mononuclear cell population comparable with pre-IL-2 treatment samples.
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