Example sentences for: eotaxin

How can you use “eotaxin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Not only are many novel genes differentially expressed in this disease model identified by microarray, but also many known genes which include many previously observed as regulated in asthma (for example those for eotaxin and VCAM-1) or regulated by relevant stimuli, such as IL-4, in cellular systems (for example, VCAM-1, C3).

  • More specifically, MCP-1 [ 2, 16], MCP-3 [ 2, 18], eotaxin [ 16, 18], pulmonary and activation-related chemokine (PARC) [ 19], and vascular cell adhesion molecule 1 (VCAM-1) [ 15] have been identified as mediators of pulmonary inflammation in asthma or relevant animal models.

  • Importantly, several of these genes - those for eotaxin [ 20], VCAM-1 [ 21], MCP-1 [ 22] and MCP-3 [ 20] - were previously known to be inducible by IL-4 in cells relevant to pulmonary inflammation, and this regulation is corroborated here in vivo in the pulmonary tissue of a non-human primate.

  • Thus the genes most highly induced in multiple monkeys 4 h after allergen challenge were those for: MCP-3 (400-fold), MCP-1 (14-fold), eotaxin (13-fold), thrombospondin (8-fold), PAI-1 (5-fold), and alpha 1 -antichymotrypsin (4-fold).

  • We screened for the presence of Th2 cells by assessing T cell expression of CCR4—a receptor for eotaxin/CCL11, macrophage chemoattractant protein 3 (CCL7), and thymus- and activation-regulated chemokine (CCL17) [40,41]—and CCR3, a receptor for eotaxin and related chemokines.


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