Words similar to enhancing
Example sentences for: enhancing
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To reduce APV pill burden and possibly improve tolerability of APV treatment, pharmacokinetic research efforts have been directed at combining APV with the PI ritonavir (RTV), which inhibits CYP3A4-mediated hepatic metabolism of APV, thereby enhancing plasma APV exposure [ 13 14 15 ] . The administration of RTV at the clinically sub-therapeutic dosage of 100 mg BID was found to boost APV plasma exposure to such a degree as to permit halving the APV daily pill burden from 16 to 8 capsules/day, in addition to maintaining the minimum plasma APV concentration (C min ) over 24 hours well above the 50% inhibitory concentrations (IC 50 ) of patient-derived HIV-1 isolates [ 15 ] . A pharmacokinetic study in 20 HIV-infected patients, PROF1004, showed that APV at the lower dosage of 600 mg BID combined with RTV 100 mg BID (APV600/RTV) resulted in a geometric mean steady-state APV C min (1.
In the 1970s, Stoppard augmented his play writing with screenwriting, enhancing his highbrow reputation by supplying scripts for auteurs Rainer Werner Fassbinder and Joseph Losey.
Maximum enhancement of NK mediated cytotoxicity was observed with a combination of IL-12 and IL-2, the effect of the two cytokines together being additive [ 2 ] . Another study revealed that cytokine stimulated NK cells use both granzyme/Fas ligand pathways of apoptotic induction to mediate cytotoxicity [ 3 ] and it was found that IL-2 and IL-12 both increase induction in mRNA coding for perforin/ granzymes A and B [ 4 ] . Hence the importance of both these cytokines in enhancing cytotoxicity cannot be overlooked.
The Acly reaction enhances FA synthesis by providing more acetyl CoA and NADPH substrates and enhancing ACC activity.
Dietary phytoestrogens sex reversed VSM, as expressed in the radial-arm maze by enhancing spatial memory in females but inhibited this ability in males, this finding corresponds to research regarding increased dementia observed in aged men consuming high tofu levels [ 44 ] . However, while it is important to establish the influence of dietary phytoestrogens on brain function and behavior in animal models, the true significance in humans remains to be determined as it relates to the present findings.
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