Example sentences for: enhancers

How can you use “enhancers” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Replication enhancers in fruit flies control the programmed amplification (extra rounds of replication in non-cycling cells) of chorion gene clusters on the third and X chromosomes.

  • For example, discrete enhancers that control embryonic expression of eve are contained within discrete CNCS clusters in the region 5' to eve (Figure 2).

  • More recently, transgenic mice have also been used to express Cre recombinase to mediate the conditional deletion of loxP -flanked DNA sequences in specific cell types in vivo . Traditional methods for generating transgenic mice require the availability of well characterized transcriptional regulatory elements, promoters or enhancers, that direct transgene expression in specific cell types.

  • In contrast, discrete CNCSs clusters are not observed in the region 3' to eve where enhancers overlap one another [ 50, 51].

  • Possible explanations for such cases include duplications which we may have missed, mutations in unknown enhancers or translation modifiers hidden in exons or introns, mutations that create novel splice sites and changes in the coding region which might be pathogenic but which, due to our lack of knowledge, are thought to be polymorphic.


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