Example sentences for: elucidation

How can you use “elucidation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • (1) These data can lead to elucidation of the complete activation profiles of these ligands, leading to clarification of the mechanisms involved in physiological effects of these ligands at δ opioid receptor.

  • In addition, unidentified cytokine-mediated mechanisms undoubtedly await elucidation.

  • Recent elucidation of the genetic ‘programming’ of the enzymes has opened a new field of drug discovery based on rationally engineering the enzymes to produce ‘unnatural natural products’ with novel properties.

  • It has been noticed that if a patient is suspected of having a mitochondrial disease, abnormal carnitine esters may help with the diagnosis, [ 38 ] and abnormal acylcarnitine profiles do not exclusively indicate fatty acid oxidation disorders [ 39 ] . Although the abnormal carnitine ester present in the proband is elevated in organic acidemias and is not usually present in mitochondrial cytopathies, we speculate that due to compromised ATP synthesis, secondary alterations may be generated in these patients by changes in mitochondrial protein synthesis, decrease in Krebs cycle intermediates and increased free radical formation, that could be responsible for a secondary impairment of mitochondrial biotin dependent carboxylases, but further elucidation is necessary before we could arrive to a conclusion in this regard.

  • Several recent papers [ 6 7 9 ] as well as ours have taken only the very first steps in applying computational approaches to the the elucidation of cis- regulatory modules.


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