Example sentences for: elucidated

How can you use “elucidated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The causative factors have not yet been elucidated by research, so we do not know what the goals are.

  • The transcription factor E2F is an important regulator of the G1/S phase transition in metazoans and a major target of the tumor suppressor Rb [ 10 ] [ 11 ] . The mechanisms controlling E2F activity have not been completely elucidated.

  • The molecular signals required for osteoclastogenesis have recently been elucidated [ 1 4 5 ] . Receptor-activator of NFκB ligand (RANKL), a tumor necrosis factor superfamily ligand expressed by stromal cells, osteoblasts, and activated T cells, binds to its cognate receptor-activator of NFκB (RANK) receptor on macrophages/monocytes, inducing a signal that gradually transforms the macrophages into osteoclasts over a period of several days [ 6 7 ] . While this interaction occurs largely in the bone microenvironment, it has been shown that monocytes from the spleen, peripheral blood, and synovium are all capable of RANKL-dependent osteoclast formation [ 8 ] . Convincing evidence has been generated indicating that the RANK-RANKL interaction is absolutely required for osteoclastogenesis [ 7 ] ; in the absence of these molecules, osteoclastogenesis cannot occur [ 9 ] .

  • This is in accordance with previous results from the field of gastroenterology and hepatology showing that a large proportion of papers originating from the UK appeared in British journals [ 9 ] . The reasons for this observation remain to be elucidated.

  • The precise role(s) of any of the identified genes in the intracellular survival of mycobacteria remain to be elucidated.


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