Example sentences for: elucidate

How can you use “elucidate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To elucidate the mechanisms used by tubercle bacilli to survive in macrophages, researchers at several laboratories are studying mycobacterial genes specifically expressed during growth in macrophages [ 1 2 3 4 5 6 ] . Among the genes specifically expressed during intracellular growth are genes encoding two extracytoplasmic function sigma factors, SigE (σ E) and SigH (σ H) [ 3 4 5 ] . Sigma factors play critical roles in the recognition of promoters by RNA polymerase.

  • H441 cells resemble bronchiolar epithelial Clara cells in phenotype and produce both SP-A and SP-B mRNA and protein [ 14 ] . The hormonal regulation of SP-A and SP-B gene expression in H441 cells is similar to that observed in differentiated type II cells in human fetal lung explants [ 6 7 15 16 ] . We treated H441 cells with the four inhibitors of signal transduction: wortmannin, LY294002, rapamycin and PD98059, to elucidate which signaling pathways are activated when insulin inhibits SP-A gene expression.

  • Further analysis of these transcripts is needed and it will remain a challenging task to elucidate the biological significance of all of them.

  • These results can help to elucidate the mechanism by which SHRs in general, and AR in particular, regulate gene expression.

  • We analyzed the repertoire and distribution of rearranged VH genes to elucidate B lymphocyte involvement in AS, and to investigate similarities to and differences from RA.


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