Words similar to egfrs

Example sentences for: egfrs

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This lack of response appears to be due to the down-regulation of EGFRs from these cells as confirmed by immunoblots using the anti-EGFR antibody (data not shown).
Various EGFRs were transiently expressed in 293T human embryonic kidney cells as published [3].
Gefitinib inhibited the activity of wild-type and L858R EGFRs progressively with increasing concentrations of drug, as demonstrated by a reduction of tyrosine-phosphorylated proteins (Figure 4A) and a decrease in p-EGFR:t-EGFR ratios (Figure 4B).
Importantly, we find that the T790M mutation confers drug resistance not just to wild-type EGFR but also to mutant EGFRs associated with clinical responsiveness to EGFR tyrosine kinase inhibitors [1,2,3].
By contrast, wild-type and mutant EGFRs containing the T790M mutation did not display a significant change in either phosphotyrosine induction or p-EGFR:t-EGFR ratios (Figure 4A and 4B).