Words similar to ecm
Example sentences for: ecm
How can you use “ecm” in a sentence? Here are some example sentences to help you improve your vocabulary:
The findings presented here, suggesting that different ECM signaling pathways are active in different cancers, could have important clinical implications, as knowledge of the specific pathways dysregulated in a particular cancer may be valuable for devising effective therapy that targets those pathways.
Four PAR'S have been identified (PAR 1-4); PAR'S 1,3 and 4 are activated by thrombin while PAR2 is activated by trypsin [ 30 ] . Activation of PAR'S may alter ECM composition.
SCm = RCm + ECm + fm * ACm + vm * ACm (2)
Thus, the differential response seen here is presumably due to the state of the ECM immediately after IL-1 exposure.
The ability of cancer cells to proliferate within a tissue depends on their response to adhesive and growth factor cues within the ECM [ 10 ] , and self-sufficiency in growth signals is one of the hallmarks of cancer [ 11 ] . To stimulate their own growth and proliferation in tissue, tumor cells can overproduce and release their own growth factors or obtain them from the matrix as they are released by matrix metalloproteinases [ 12 ] . The endothelial vasculature grows into the tumor and provides nutrients and oxygen [ 13 ] . This model is illustrated by the experimental results presented here, as both A549 (lung) and U118 (brain) cell lines are observed to upregulate one set of genetic programs related to cell growth and proliferation when in culture and another set related to cell adhesion, the extracellular matrix, growth substances, and neovascularization when developing as an in vivo tumor.
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