Example sentences for: ecs

How can you use “ecs” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To better understand molecular mechanisms and pathways of EC activation, we embedded ECs in 3D type I collagen in presence or absence of human recombinant VEGF 165.

  • Consistent with this, incubation of ECs with angiogenic cytokines induced the expression of MMP-1 and MMP-2 (Figs.

  • We believe, this is the first report of identification of BTF3 as one of the induced genes in the activation of ECs.

  • The function of epiregulin in the activation of ECs has not been investigated.

  • Mediators known to activate ECs include inflammatory cytokines, growth factors such as VEGF/VPF and basic fibroblast growth factor (bFGF), extracellular matrix (ECM) proteins such as collagen and fibronectin, and proteases such as MMPs [ 1 2 ] . In vitro and in vivo assays indicate that VEGF signaling promotes increased permeability, cell migration, proliferation, and differentiation, functioning through two EC-specific tyrosine kinase receptor such as Kinase domain receptor (KDR) [ 1 2 3 ] . In the majority of solid tumors, VEGF is upregulated in response to hypoxia, inducing the expression of pro-angiogenic genes that promote tumor angiogenesis, growth and eventual metastasis [ 3 4 5 ] . The expression of both positive and negative factors must be tightly and specifically regulated in a coordinated manner.


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