Example sentences for: dmd

How can you use “dmd” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The purpose of this project was to develop an effective and convenient process to detect both large and small alterations in the DMD gene with only a moderate increase in cost.

  • A major consequence of the dystrophin gene's large genomic size is a high rate of mutation; close to 30% of cases prove to be spontaneous mutations [ 5 ] . Approximately 60% of mutations causing DMD are deletions of large segments of the gene usually including one or more exons [ 6 7 8 ] . Approximately 5% of mutations are duplications of large segments of the gene [ 8 ] . Large deletions and duplications are detected using multiplexed PCR primers to amplify a subset of (approximately 20 of the 79) exons that are empirically estimated to constitute 98% of large deletions and duplications.

  • For example, a profile from DMD patient 9 (9a) clustered with the normal controls, rather than with the other DMD patients (Fig.

  • To test the sensitivity and specificity of sample mixing versus individual profiling, we defined differentially expressed genes using a two group t-test (GeneSpring [ 28 29 ] ), comparing all 6 mixed control profiles and the 10 individual 5-6 yr old DMD profiles.

  • The detection rate for all mutations in the DMD gene can be increased from the present 65% to above 92%.


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