Words similar to dmd
Example sentences for: dmd
How can you use “dmd” in a sentence? Here are some example sentences to help you improve your vocabulary:
The purpose of this project was to develop an effective and convenient process to detect both large and small alterations in the DMD gene with only a moderate increase in cost.
A major consequence of the dystrophin gene's large genomic size is a high rate of mutation; close to 30% of cases prove to be spontaneous mutations [ 5 ] . Approximately 60% of mutations causing DMD are deletions of large segments of the gene usually including one or more exons [ 6 7 8 ] . Approximately 5% of mutations are duplications of large segments of the gene [ 8 ] . Large deletions and duplications are detected using multiplexed PCR primers to amplify a subset of (approximately 20 of the 79) exons that are empirically estimated to constitute 98% of large deletions and duplications.
For example, a profile from DMD patient 9 (9a) clustered with the normal controls, rather than with the other DMD patients (Fig.
To test the sensitivity and specificity of sample mixing versus individual profiling, we defined differentially expressed genes using a two group t-test (GeneSpring [ 28 29 ] ), comparing all 6 mixed control profiles and the 10 individual 5-6 yr old DMD profiles.
The detection rate for all mutations in the DMD gene can be increased from the present 65% to above 92%.
Loading...