Words similar to dmd
Example sentences for: dmd
How can you use “dmd” in a sentence? Here are some example sentences to help you improve your vocabulary:
After reviewing medical records, we studied eight male patients who had been diagnosed as having DMD based on pathology lab report, disease progression and abnormalities in the level of dystrophin expression either by immunofluorescence or western blot analysis.
The purpose of this project was to develop an effective and convenient process to detect both large and small alterations in the DMD gene with only a moderate increase in cost.
A major consequence of the dystrophin gene's large genomic size is a high rate of mutation; close to 30% of cases prove to be spontaneous mutations [ 5 ] . Approximately 60% of mutations causing DMD are deletions of large segments of the gene usually including one or more exons [ 6 7 8 ] . Approximately 5% of mutations are duplications of large segments of the gene [ 8 ] . Large deletions and duplications are detected using multiplexed PCR primers to amplify a subset of (approximately 20 of the 79) exons that are empirically estimated to constitute 98% of large deletions and duplications.
In parallel, we compared the two corresponding mixed 5-6 yr old DMD profiles to the same 6 mixed control profiles.
In parallel, the mixed DMD duplicate profiles were compared to a single pair of mixed control sample profiles (c1a, c1b), using the pairwise comparison survival method [ 23 ] . Briefly, four comparisons were done (DMD 1a versus control 1a; DMD1b versus control 1a; DMD 1a versus control 1b; DMD1b versus control 1b), and only those genes retained which showed >2-fold change in all four comparisons.
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