Words similar to desmin
Example sentences for: desmin
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These included histone H4, which did not exhibit differential expression in the two tissues (log 2 ratio around 0); cytochrome oxidase IV, kynurenine 3-hydroxylase, serine/threonine protein kinase and 14-3-3 protein gamma which exhibited two- to threefold differences (log 2 ratio = 1 to 1.6); and desmin which was around 32-fold differentially expressed between the two tissues (log 2 ratio approximately 5).
As several IF proteins, including desmin, have been implicated in human genetic disorders such as dominant and recessive congenital and adult onset myopathies [ 15, 16, 17, 18], desmuslin becomes a candidate to be involved in myopathies as well.
Desmuslin is hypothesized to function as a mechanical support to the muscle myofibers by making a previously unrecognized linkage between the extracellular matrix via the DAPC and the Z-discs through desmin and plectin [ 14].
Electron microscopic analysis shows that desmuslin colocalizes with desmin, another muscle IF protein.
For the oligonucleotides corresponding to differentially expressed genes (for example, SCG10, desmin, 14-3-3-gamma, profilin ), the log 2 ratios from four independent hybridizations (including flip dye experiments) were averaged and plotted in Figure 7b.
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