Example sentences for: desmuslin

How can you use “desmuslin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The generation of desmuslin null animal models will also contribute to the understanding of the role of this protein in muscle and cardiac disease.

  • The C598T DMN mutation is a good candidate to be a modifier for muscular and/or cardiac phenotypes, considering: (i) the frequency of the mutation in the normal population in the heterozygous as well as homozygous state; and (ii) the key role of desmuslin in connecting the Z-discs to the extracellular matrix.

  • The desmuslin coding sequence is highly polymorphic with 9 SNPs that do not alter an amino acid and 12 that do.

  • Desmuslin is hypothesized to function as a mechanical support to the muscle myofibers by making a previously unrecognized linkage between the extracellular matrix via the DAPC and the Z-discs through desmin and plectin [ 14].

  • DAPC: Dystrophin-associated protein complex; DMN: Desmuslin, SNP: Single-nucleotide polymorphism; IF: Intermediate filament


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