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Example sentences for: denatonium

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Rat T1R2/T1R3 recognized sweet-tasting molecules as diverse as acesulfame-K, dulcin, NC00174 (GA2), saccharin, SC45647 (GA1) and sucrose [ 6 ] , and mT2R-8 and-5 responded to the bitter compounds denatonium, 6-n-propyl-2-thiouracil and cycloheximide respectively [ 17 ] . Thus, although it is clear that the murine taste world in many ways differs from that of humans, the taste of the compounds used here to the mouse seems to be similar to their taste in human.
Recent behavioral experiments in rats stress the prominence of the CT over the NG for the bitter taste [ 26 27 28 ] . We have found that mice with bilateral CT cut have a significantly impaired ability to discriminate water from the bitter stimulus denatonium benzoate in two bottle preference (TBP) tests, while mice with bilateral NG cut showed no difference from the sham surgery group (own unpublished observations).
1, 20 mM denatonium and 10 mM PROP elicited a small phasic response in the CT in the mouse MO01F22.
This suggests that a small phasic response in the CT to denatonium benzoate might be at least as important as the large NG response for the decisions to be made in TBP tests.
Compounds comprising the first group, cycloheximide, denatonium benzoate and PROP, elicited strong responses in the NG and no significant responses in the CT.