Words similar to deleterious
Example sentences for: deleterious
How can you use “deleterious” in a sentence? Here are some example sentences to help you improve your vocabulary:
[ 1 ] ). By contrast, if deleterious mutations interact so that their combined effect is smaller than expected under the multiplicative model, then epistasis is called antagonistic (or positive in the terminology of Phillips et al.)
Since no primary deleterious mtDNA mutation has been found in the proband and she was born to healthy parents with unremarkable family history, we hypothesize that the etiology of her mitochondrial dysfunction could reside in a still unidentified nuclear gene defect; although secondary mitochondrial dysfunction caused by an unknown inborn error of metabolism cannot be excluded completely.
The plasminogen activators, tissue type and urokinase type, have been reported to be both deleterious in inflammation, owing to the proteolysis of tissue proteins, and beneficial because of fibrinolytic activity [ 26 ] . The presence of both increased urokinase and plasmin inhibitors in rheumatoid arthritis synovial tissue suggests a complex role for urokinase in this disease [ 27 28 29 ] that seems pertinent to our finding of urokinase-generated mactinin in the arthritis fluid samples.
The overall effect of urokinase in the antigen-induced arthritis model seems to be beneficial, because chronic joint inflammation and bone erosion are significantly worse in urokinase-deficient mice [ 30 ] . However, the ability of urokinase-generated mactinin to enhance proteolysis might be deleterious.
Despite the decrease in hepatocellular proliferation caused by RU 486, inhibition of hepatic apoptosis in animals treated with this compound (Fig 1B) represents a potentially deleterious effect.
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