Words similar to deleterious

Example sentences for: deleterious

How can you use “deleterious” in a sentence? Here are some example sentences to help you improve your vocabulary:

The nearly neutral theory of evolution (Ohta 1973) predicts accelerated fixation of deleterious mutations through random genetic drift in small populations, a phenomenon that has been observed in endosymbionts (Moran 1996; Lambert and Moran 1998).
However, the most obvious models for the deleterious effects of aneuploidy should instead depend on the total number of genes.
In the report by Chasman and Adams, evolutionary information was predicted to be a useful component in determining whether a mutation is deleterious [ 13 14 ] . Disease causing mutations are also likely structurally perturbing at the protein level [ 15 ] . Ng and Henikoff have introduced SIFT, a method for predicting functional SNPs from a database of unannotated polymorphisms [ 16 17 ] .
In a mutational analysis of the same triad in the aI5γ intron, it was found that mutations at G3 were some of the more deleterious ones in DV [ 19 ] . Revertants that restored base pairing were also identified.
The overall effect of urokinase in the antigen-induced arthritis model seems to be beneficial, because chronic joint inflammation and bone erosion are significantly worse in urokinase-deficient mice [ 30 ] . However, the ability of urokinase-generated mactinin to enhance proteolysis might be deleterious.