Example sentences for: deleterious

How can you use “deleterious” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In some strains, cells with [PSI + ] prion demonstrated better survival than their non-prion counterparts in the presence of inhibitors of translation or microtubules, heavy metals, low pH, and other deleterious conditions, which of course gives a strong advantage to the [PSI + ] cells.

  • With a continuous fitness scale, apart from neutral and inviable sequences, we would have to keep track of slightly and strongly deleterious as well as advantageous sequences, and would consequently need a much more elaborate mathematical procedure to account for the contributions from these different fitness classes.

  • We have shown that phenotypic hiding has substantial influence on the equilibrium frequencies of mutants in selection-mutation balance, and on the speed at which deleterious mutants are lost from the population.

  • However, some particular cases have been studied [ 30 31 32 ] , mostly related to recombination and reassortment [ 33 34 35 36 ] and to the dynamic of defective interfering particles [ 37 38 39 40 41 ] . In this paper, we modify the quasispecies model by incorporating phenotypic hiding between wild-type virus and a deleterious mutant.

  • Perhaps down-regulation of frizzled family members by IL-1β is deleterious to chondrocyte function and can contribute to OA.


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