Words similar to deleterious

Example sentences for: deleterious

How can you use “deleterious” in a sentence? Here are some example sentences to help you improve your vocabulary:

Recently, it has been demonstrated that the magnitude of the fitness effects associated with deleterious mutations in protein-coding genes (i.e.
However, genomes also show signs of deleterious deletions.
In the report by Chasman and Adams, evolutionary information was predicted to be a useful component in determining whether a mutation is deleterious [ 13 14 ] . Disease causing mutations are also likely structurally perturbing at the protein level [ 15 ] . Ng and Henikoff have introduced SIFT, a method for predicting functional SNPs from a database of unannotated polymorphisms [ 16 17 ] .
However, if a fitness function grows at a less than exponential rate, then a relaxation of selection against deleterious mutations is expected [ 68, 69, 70, 71].
The challenge of utilizing this technique for the creation of subunit vaccines for the human population will be to create T cell epitopes within a protein of interest that will not have deleterious effects on the activity or the stability of the protein of interest, and that would be effective across a number of HLA-DR haplotypes [ 39 ] .