Words similar to deleterious
Example sentences for: deleterious
How can you use “deleterious” in a sentence? Here are some example sentences to help you improve your vocabulary:
In some strains, cells with [PSI + ] prion demonstrated better survival than their non-prion counterparts in the presence of inhibitors of translation or microtubules, heavy metals, low pH, and other deleterious conditions, which of course gives a strong advantage to the [PSI + ] cells.
With a continuous fitness scale, apart from neutral and inviable sequences, we would have to keep track of slightly and strongly deleterious as well as advantageous sequences, and would consequently need a much more elaborate mathematical procedure to account for the contributions from these different fitness classes.
We have shown that phenotypic hiding has substantial influence on the equilibrium frequencies of mutants in selection-mutation balance, and on the speed at which deleterious mutants are lost from the population.
However, some particular cases have been studied [ 30 31 32 ] , mostly related to recombination and reassortment [ 33 34 35 36 ] and to the dynamic of defective interfering particles [ 37 38 39 40 41 ] . In this paper, we modify the quasispecies model by incorporating phenotypic hiding between wild-type virus and a deleterious mutant.
Perhaps down-regulation of frizzled family members by IL-1β is deleterious to chondrocyte function and can contribute to OA.