Words similar to deleterious
Example sentences for: deleterious
How can you use “deleterious” in a sentence? Here are some example sentences to help you improve your vocabulary:
An additional argument for calling all these mutations compensatory is that they can produce a fitness gain only in association with one or more mutations that would otherwise be deleterious, that is, none of the mutations that could be termed advantageous is accessible directly from the main neutral network.
Should this be the case, however, a duplication event would only very rarely achieve fixation [ 28, 29]; moreover, in the event that a duplication is slightly deleterious, it would be effectively prevented from achieving fixation [ 30].
The challenge of utilizing this technique for the creation of subunit vaccines for the human population will be to create T cell epitopes within a protein of interest that will not have deleterious effects on the activity or the stability of the protein of interest, and that would be effective across a number of HLA-DR haplotypes [ 39 ] .
This unconstrained paralog is then free to accumulate neutral mutations that would have been deleterious in a unique gene [ 1].
Febrile seizures are the most prevalent type of seizures experienced by children, affecting up to 5% of the world's population [ 1 ] . Although most febrile seizures are benign and do not require treatment, they are distressing to parents, and in a few circumstances, can increase the risk of subsequent epilepsy [ 2 ] . In clinical practice, therapy for febrile seizures presently is unsatisfactory, since clinical data are insufficient to document efficacy of most anti-epileptic drugs [ 3 ] . The most commonly used drug, phenobarbital, has significant deleterious effects on learning and behavior.
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