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Example sentences for: deleted

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pTX-MKA1, pMKB-GFP, pTX-MKC1 were transformed into either Ax2 cell line [ 37 ] or HS1 myosin null cells, a strain of D. discoideum with its endogenous mhc A gene deleted [ 38 ] to generate GFP-MHCK-A, -B, and -C cells, respectively.
At present, we cannot exclude that residues outside the F-box mediate binding of F-box deleted Pop2p to Psh1p and other core subunits.
In several cell lines, particularly in pancreatic carcinoma cells, resistance to TGFβ 1 could be attributed to a loss of function of the SMAD4 (DPC4) protein [ 40 41 42 43 ] . However, the pancreatic carcinoma cell line BxPC-3, although homozygously deleted for SMAD4, is growth inhibited by TGFβ 1 [ 30 44 ] . It is thus speculated that alternative signaling pathways in addition to the SMAD pathway may exist.
The deleted region is not conserved in hTAF II 105 and dTAF II 110, is not involved in interactions with other TAF II s, SP1, or CREB [ 26, 27, 33], and has no known function.
In order to generalize the integrin mediated TGFβ 1 -pathway identified in the SMAD4 deleted pancreatic tumor cell line BxPC-3, we investigated TGFβ 1 signaling in the cervical carcinoma cell line HeLa and the mammary carcinoma cell lines MCF-7 and MDA-MB-231, harboring a wildtype SMAD4-gene.