Words similar to defective
Example sentences for: defective
How can you use “defective” in a sentence? Here are some example sentences to help you improve your vocabulary:
More recent observations support an alternative mechanism of action for the PrlA/SecY and PrlG/SecE suppressors [ 8 12 ] . First, PrlA/G-mediated suppression does not exhibit allele specificity; all prlA and all prlG alleles that have been examined suppress all signal sequence mutations, implying that suppression is not due to a specific altered interaction that allows recognition of a mutant signal sequence [ 8 12 ] . Furthermore, all of the prlA and prlG alleles suppress complete deletions of the signal sequence, suggesting that an interaction between the signal sequence and the Prl suppressor is not necessary for suppression or even for export [ 5 8 13 ] . Based on these observations, it was proposed that the PrlA and PrlG suppressors do not function through altered interactions with signal sequences, but rather by loss of recognition [ 8 12 ] . The wild type SecE and SecY proteins are thought to function in concert to proofread the signal sequence of secretory proteins, rejecting defective precursors from the export pathway.
These results confirm that the kinase defective IGF-IR is able to inhibit tumor growth in a model system.
For example, T59A and T59S are both repressor-defective in vivo [ 7, 10], although there seems to be some disagreement as to exactly how defective T59S is for RNA binding in vitro [ 7, 11].
Nearsightedness, the ability to see near things more clearly than distant ones, is basically defective vision of distant objects.
The AVM's lineal mother and grandmother both migrate anteriorly and if either of these migrations were defective, the AVMs would be mispositioned.
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