Words similar to defective
Example sentences for: defective
How can you use “defective” in a sentence? Here are some example sentences to help you improve your vocabulary:
Net1 is unlikely to directly regulate transmission of the tester chromosome, because it is only localized to rDNA in the nucleolus [ 15 16 17 ] . Thus, the difference between net1 tab 2-1and CDC14 TAB 6-1presumably results from molecular defects unique to the former mutant, including defective nucleolar structure and function, or perhaps defective nuclear transport ( [ 18 ] ; Figure 6).
Classic examples include Archibald Garrod, a British physician whose desire to understand why a patient produced black urine led to the hypothesis that diseases can result from defective metabolic enzymes, and Fuller Albright, a clinical investigator at Harvard whose thoughtful approach to his patients yielded insights that revolutionized the field of endocrinology.
School of Medicine researchers and physicians have: developed treatments that turned a 90 percent mortality rate for testicular cancer into a 90 percent cure rate; pioneered echocardiography, we use of sound waves for detecting heart disease; shared in developing "smart" pacemakers, which monitor heart rhythm and automatically shock the heart when it develops irregularities; founded the world's first DNA bank, preserving genetic material for future study and diagnosis; pinpointed the defective gene in Huntington's disease and one type of Alzheimer's disease; and spearheaded the use of many New treatments for critically ill children, including infant heart transplant and special therapies for cancer.
Differences in the phenotypes would be due to inherent differences in the sensitivity of these cell types to the defective organizing centers.
Indeed, it has been estimated that the deleterious mutation rate in viruses that replicate using RNA polymerases (either reverse transcriptase in the case of retroviruses or RNA-dependent RNA polymerase for other RNA viruses) is on the order of one error per replication cycle, so that many of the viral progeny produced by replication are defective (Elena and Moya 1999).
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