Example sentences for: defect

How can you use “defect” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As was true in sea urchin embryos [ 30, 31], titration of transcription factors with high copy transgenes may be useful for characterizing control elements in C. elegans . The ALM migration defect should be useful for identifying optimal conditions for the titration of DNA binding protein with high copy arrays.

  • pJC16 arrays induced fewer migration defects than pJC14 arrays and pJC17 arrays induced fewer migration defects than pJC16 arrays, so there appeared to be multiple sequences between the Hpa I and Bsa BI restriction sites that contributed to the migration defect.

  • Thus, the second possibility is that failure of sα i2 to localize at the PM but instead localize at intracellular membranes is the result of a general defect in protein stability.

  • Furthermore, Skp2 knockout cells show no defect in E2F-1 degradation [ 21 ] , and E2F-1 proteins unable to interact with Skp2 are still unstable [ 20 ] . Our results implicate SCF Slmbrather than SCF Skp2in cell cycle specific destruction of E2F and argue that this regulation is critical for cell viability at least in flies.

  • In vitro studies with dermal fibroblasts isolated from SPARC-null mice further showed that the ability of the cells to restore wounded areas was hindered and that a defect in cell migration, rather than cell proliferation, was the major cause of the delay in repopulating the denuded area.


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