Example sentences for: cyclases

How can you use “cyclases” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We also identify the potential active site- and substrate interacting-residues and postulate that these enzymes are likely to catalyze a two-metal ion dependent reaction on structural scaffold that is completely different from that seen in the other two superfamilies of adenylyl cyclases.

  • We postulate that these enzymes are likely to chelate 2 divalent cations and are likely follow a bimetal reaction mechanism similar to what has been proposed for nucleotide cyclases, nucleic acid polymerases, or certain phosphoesterases such as those of the HD and DHH superfamilies.

  • Using sequence profile searches we identify two conserved domains in the N-terminal extensions of the soluble guanylyl cyclases from animals.

  • PSI-BLAST searches initiated with the C-terminal part of the SGC-specific extension (the region in between the above-detected N-terminal-most domain, and the C-terminal cyclase domain; human SGC1β, region: 200-370) recovered homologous regions from all other animal soluble guanylyl cyclases, and, additionally, N-terminal regions of histidine kinases from Nostoc and Anabaena species (eg.

  • The soluble guanylyl cyclases are important signaling molecules in animals that transduce signals mediated by the gaseous first messenger, nitric oxide [ 16 17 18 19 ] . In animals, NO functions as a neurotransmitter both in the central and peripheral nervous system.


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