Example sentences for: cyclase

How can you use “cyclase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • HD domains typically possess phosphoesterase activity, and are fused to catalytic domains that possess nucleotide kinase, nucleotidyltransferase, nucleotide cyclase or diguanylate cyclase activity [ 19 29 ] . This fits well with the observed cyclase activity seen in CyaB, but is also consistent with phosphotransferase or nucleotidyl transferase for the CYTH domain.

  • These inhibitory actions of 4-AP on adenylate cyclase activity, StAR expression and steroidogenesis may reflect drug-induced changes in the intracellular concentrations of K +and Cl -and the GC resting membrane potential.

  • , 1996 [ 3 ] ). For example, some classical neurotransmitters such as 5-HT have short-term effects on ion channels and other effectors such as adenylyl cyclase but also have growth factor-like effects in developing brain [ 4 ] and mitogenic effects on fibroblasts (reviewed in Gerhardt and van Heerikhuizen, 1997 [ 5 ] ). The peptide hormones insulin and IGF-1 have both short-term metabolic effects and long-term actions on cell growth and differentiation.

  • Based on these two sets of results, if the analgesic effect of butorphanol is mediated via μ opioid receptors through the inhibitory effect of these receptors on adenylyl cyclase, the equal efficacy of morphine and butorphanol would support an equal antinociceptive effect of these two drugs.

  • On the other hand, PGI 2 decreases vascular smooth muscle cell proliferation and collagen and glycosaminoglycane synthesis, via activation of adenylyl cyclase and subsequent production of cAMP [ 17 ] . Betaprost, an analog of PGI 2 , decreases procollagen I and III mRNA expression in cardiac fibroblasts [ 18 ] . These effects may counteract the profibrotic effects seen with TXA 2 and it is possible that an alteration of a "normal" physiologic balance between PGI 2 and TXA 2 could increase tendency towards fibrogenesis.


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