Words similar to cyclase
Example sentences for: cyclase
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Activation of the ionic current was induced by preincubation of AQP1-expressing oocytes for 10-30 minutes in 10 mM 8Br-cGMP (Sigma) in high K +saline, containing (in mM): 30 KCl, 80 K gluconate, 5 MgCl 2 , 5 HEPES, pH 7.3, or by addition of 2-4 mM sodium nitroprusside (SNP), a stimulator of guanylate cyclase and cGMP production [ 34 35 ] . Control oocytes treated in the same conditions showed no induction of an ionic current.
Genes encoding practically all the solo versions of the HNOB domain occur in the same predicted operon as a histidine kinase or a GGDEF domain (diguanylate cyclase) [ 33 34 35 ] . In some cases these operons also encode receiver domain proteins of the two component systems, PP2C phosphatases or cyclic diguanylate phosphodiesterases (Fig.
Metabotropic glutamate receptors (mGluRs) are a family of class 3 G protein-coupled receptors with important functions in the regulation of synaptic transmission, plasticity, neuronal excitability, and the regulation sensory transduction [ 1 2 3 4 5 ] . The eight mGluRs (mGluR1-8) and their splice variants have been divided into three groups (I-III) based on sequence homology, pharmacology and G protein coupling profiles [ 3 6 7 ] . Group II (mGluR2 and 3) and III (mGluR4, and 6 through 8) couple negatively to adenylate cyclase through activation of the G i/o family of G proteins [ 8 ] . Group I mGluRs (mGluR1 and 5) couple to multiple G proteins in native and heterologous systems, and have been observed to couple to G q/11 , G i/o and/or G s [ 9 10 11 12 13 14 15 ] . mGluRs appear to be important mediators of synaptic transmission in the brain.
As in the pheromone response and cell wall integrity network models, key components of the Ras GTPase are included, such as Cdc25p (the Ras guanine nucleotide exchange factor), Cyr1p (the Ras-associated adenylate cyclase), and Srv2p, which enables the activation of adenylate cyclase by Ras2p.
HD domains typically possess phosphoesterase activity, and are fused to catalytic domains that possess nucleotide kinase, nucleotidyltransferase, nucleotide cyclase or diguanylate cyclase activity [ 19 29 ] . This fits well with the observed cyclase activity seen in CyaB, but is also consistent with phosphotransferase or nucleotidyl transferase for the CYTH domain.
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