Example sentences for: cyclase

How can you use “cyclase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Intracellular signaling machinery of adenylyl cyclase is required for cytoskeletal organization, vessel maturation, and vessel integrity [ 24 ] . PF4 is a chemokine that binds to FGF and is a known inhibitor of EC proliferation and migration [ 25 ] . Thus, the upregulation of PF4 might limit the degree of activation of ECs and morphogenic differentiation.

  • NO is released by a cell through the action of the nitric oxide synthase (NOS) on its substrate, the amino acid arginine [ 20 ] . NO diffuses through the neighboring cells and elicits its functions by activating a soluble guanylyl cyclase (SGC) that synthesizes cGMP using GTP as a substrate [ 16 18 ] . The animal SGCs are dimeric enzymes comprised of two homologous subunits, α and β.

  • Although β-adrenoceptor desensitization [ 23] or reduced ATPase activity [ 25] may account for the decrease in basal heart rate in the hypertrophied male hearts, the increased sensitivity to isoproterenol may support the hypotheses of ischemia-induced activation of β-adrenoceptor kinase [ 26] or modulation of G-protein signaling to preserve adenylate cyclase activity [ 27].

  • Genes encoding practically all the solo versions of the HNOB domain occur in the same predicted operon as a histidine kinase or a GGDEF domain (diguanylate cyclase) [ 33 34 35 ] . In some cases these operons also encode receiver domain proteins of the two component systems, PP2C phosphatases or cyclic diguanylate phosphodiesterases (Fig.

  • Our results clearly characterize the ligands studied as agonists or antagonists at μ opioid receptors with respect to inhibition of adenyly cyclase.


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