Words similar to cxcl

Example sentences for: cxcl

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Immunohistochemistry showed that both CXCR1 and CXCR2 were expressed by synovial macrophages and neutrophils, suggesting that the CXCL8 binding sites on these cells were CXCR1 and CXCR2.
Semi-quantitative RT-PCR using specific primers for TNF-α, MIP-2 (CXCL2) and IL-1β showed that LPS treatment caused the amount of TNF-α mRNA to slightly increase compared to the already abundant levels found in untreated cells (figure 2and 3).
For qualitative PCR, target sequences were amplified at 56°C for 25 cycles; for semi-quantitative PCR, target sequences for TNF-α, IL-1β, and MIP-2 (CXCL2) were amplified at 56°C between 22 and 32 cycles in order to yield visible products within the linear amplification range.
Because MIG/CXCL9 and IP-10/CXCL10 are chemotactic for stimulated CXCR3 expressing activated T lymphocytes, we determined if neutralizing these chemokines in vivo in the SLC/CCL21-treated mice would decrease the frequency of CXCR3 expressing T cells at the tumor sites.
Tumour necrosis factor-α blockade reduces synovial expression of CCL2 and CXCL8 and reduces inflammatory cell migration into RA joints [ 9 ] . In addition, these chemokines, produced by RA synovial stromal cells, have been shown to stimulate monocyte migration [ 10 ] . The functional importance of chemokines in joint inflammation has also been established in animal models of RA where antibodies to these mediators significantly reduce both the number of leukocytes recruited and the severity of disease.