Example sentences for: cxcl
How can you use “cxcl” in a sentence? Here are some example sentences to help you improve your vocabulary:
Because MIG/CXCL9 and IP-10/CXCL10 are chemotactic for stimulated CXCR3 expressing activated T lymphocytes, we determined if neutralizing these chemokines in vivo in the SLC/CCL21-treated mice would decrease the frequency of CXCR3 expressing T cells at the tumor sites.
Further studies are required to delineate the mechanisms responsible for MIG/CXCL9, IP-10/CXCL10 and IFNγ mediated localization of DC at the tumor site.
Neutralization of any one of these cytokines caused a concomitant decrease in all three cytokines, thus indicating that IFNγ, MIG/CXCL9 and IP-10/CXCL10 are interdependent in the SLC/CCL21-mediated anti-tumor responses.
Here we show that the cytokines IFNγ, IP-10/CXCL10 and MIG/CXCL9 serve as effector molecules in SLC/CCL21-mediated anti-tumor responses.
Tumour necrosis factor-α blockade reduces synovial expression of CCL2 and CXCL8 and reduces inflammatory cell migration into RA joints [ 9 ] . In addition, these chemokines, produced by RA synovial stromal cells, have been shown to stimulate monocyte migration [ 10 ] . The functional importance of chemokines in joint inflammation has also been established in animal models of RA where antibodies to these mediators significantly reduce both the number of leukocytes recruited and the severity of disease.