Words similar to cxcl

Example sentences for: cxcl

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Further studies are required to delineate the mechanisms responsible for MIG/CXCL9, IP-10/CXCL10 and IFNγ mediated localization of DC at the tumor site.
Compared to SLC/CCL21-treated mice receiving control antibody, flow cytometric evaluation of single-cell suspensions of non-necrotic tumors from SLC/CCL21-treated mice receiving neutralizing antibodies to MIG/CXCL9, IP-10/CXCL10 and IFNγ showed 10, 12 and 31 % decreases, respectively, in the gated CD3 CXCR3 +veT cell populations (Table 1).
Abs to murine MIG/CXCL9, IP-10/CXCL10 and recombinant cytokine standards was purchased from R&D (Minneapolis, MN).
SLC/CCL21 is documented to have direct anti-angiogenic effects [ 28 29 ] ; the tumor reductions observed in this model could have been due to participation by T cells secreting IFNγ leading to inhibition of angiogenesis via MIG/CXCL9 and IP-10/CXCL10, as well as T cell-dependent immunity [ 16 ] . IFNγ mediates a range of biological effects that facilitate anticancer immunity.
An alternative explanation is that residual cytokines such as IFN-inducible T cell α chemoattractant (ITAC/CXCL11) present after in vivo neutralization of IFNγ, MIG, IP-10 may have remaining activity and attract CXCR3 +veT cells.