Example sentences for: cxc
How can you use “cxc” in a sentence? Here are some example sentences to help you improve your vocabulary:
Varying percentages of CD4 +memory T cells expressed CC and CXC chemokine receptors as shown in Tables 4and 5. Thus, for example, 21% of RA synovial CD4 +memory T cells expressed CCR5, 39% CCRb, and 19% CCR7 mRNAs, whereas 16% expressed CXCR3 and 76% expressed CXCR4 mRNAs.
Sepsis is associated with a rapid release of CXC chemokines by alveolar macrophages, as well as up regulation of lung vascular intercellular adhesion molecule-1 (ICAM-1) expression [ 26 ] and these may contribute to the initial increase in adherent vascular neutrophils in the lung.
In the granulation tissue of burn wounds, expression of groα /MGSA and CXCR2 (the receptor for MGSA) was associated with fibroblasts, smooth muscle cells/myofibroblasts and a subpopulation of macrophages [ 7 ] . Groα/MGSA and IL-8 have also been shown to enhance re-epithelialization of human skin grafts in chimeric mice [ 29 38 ] . It has also been found that several CXC chemokines can modulate angiogenesis [ 39 ] , a process that is critical for proper healing.
Interleukin-8 (IL-8) is a potent member of the supergene family of CXC chemokines with ELR motif (ELR+).
The CXC chemokines such as IL-8 were originally identified as potent activators and chemoattractants for neutrophils, whereas the CC chemokines such as MCP-1 and RANTES mostly attract monocytes and eosinophils respectively [ 10 ] . Chemokines are secreted in a stimulus-and cell type-specific manner [ 11 12 13 14 15 16 17 ] and are regulated primarily at the level of gene transcription [ 18 19 20 21 22 23 24 ] . The transcriptional promoters of IL-8, RANTES and MCP-1 contain binding sites for the redox-responsive transcription factor NF-κB, which has been shown to be important for their regulation by viral infections and cytokines [ 18 20 23 25 26 27 28 29 30 31 32 33 34 ] .
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