Example sentences for: cxc
How can you use “cxc” in a sentence? Here are some example sentences to help you improve your vocabulary:
Several observations support the assertion that a complex interaction between IL-8 and several other growth factors, cytokines, or other proteins is responsible for these tumor-related events [ 5 9 10 11 12 13 ] . Growth regulated protein alpha (GRO-α), beta (GRO-β), and ENA-78 have been reported to be co-induced with IL-8 in A549 cells stimulated with two proinflammatory cytokines, IL-1β and TNF-α [ 14 ] . This result is consistent with the presence of nuclear factor kappa B (NF-κB) consensus binding sites in the promoter regions of all three genes [ 4 15 ] . In addition, GRO-α and -β are also members of the ELR +CXC cytokine family that are reported to be important mediators of tumorigenesis through their angiogenic properties [ 2 16 ] . They both share one of the IL-8 receptors, CXCR2, which has been postulated to regulate the ELR +CXC chemokine-mediated angiogenesis and resulting-tumorigenesis [ 1 ] . These observations suggest that GRO-α and -β may exhibit expression profiles similar to IL-8.
Sepsis is associated with a rapid release of CXC chemokines by alveolar macrophages, as well as up regulation of lung vascular intercellular adhesion molecule-1 (ICAM-1) expression [ 26 ] and these may contribute to the initial increase in adherent vascular neutrophils in the lung.
ELR +CXC chemokines are potent angiogenic factors, whereas ELR -CXC chemokines are potent angiostatic factors.
Interestingly, the analysis of abstract contents was able to distinguish monokines belonging to the CXCR family (SCYB chemokines: IP-9, IP-10, MIG; associated with 'CXC', 'CXCR', 'monokine' or 'MIG') from CC chemokines (SCYA chemokines: LARC, RANTES, MCP2, MCP3).
Varying percentages of CD4 +memory T cells expressed CC and CXC chemokine receptors as shown in Tables 4and 5. Thus, for example, 21% of RA synovial CD4 +memory T cells expressed CCR5, 39% CCRb, and 19% CCR7 mRNAs, whereas 16% expressed CXCR3 and 76% expressed CXCR4 mRNAs.
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