Example sentences for: cxc
How can you use “cxc” in a sentence? Here are some example sentences to help you improve your vocabulary:
Varying percentages of CD4 +memory T cells expressed CC and CXC chemokine receptors.
Several observations support the assertion that a complex interaction between IL-8 and several other growth factors, cytokines, or other proteins is responsible for these tumor-related events [ 5 9 10 11 12 13 ] . Growth regulated protein alpha (GRO-α), beta (GRO-β), and ENA-78 have been reported to be co-induced with IL-8 in A549 cells stimulated with two proinflammatory cytokines, IL-1β and TNF-α [ 14 ] . This result is consistent with the presence of nuclear factor kappa B (NF-κB) consensus binding sites in the promoter regions of all three genes [ 4 15 ] . In addition, GRO-α and -β are also members of the ELR +CXC cytokine family that are reported to be important mediators of tumorigenesis through their angiogenic properties [ 2 16 ] . They both share one of the IL-8 receptors, CXCR2, which has been postulated to regulate the ELR +CXC chemokine-mediated angiogenesis and resulting-tumorigenesis [ 1 ] . These observations suggest that GRO-α and -β may exhibit expression profiles similar to IL-8.
SDF-1 is a powerful CXC chemokine that recruits circulating lymphocytes, monocytes, and CD34 +hematopoietic progenitors, but not neutrophils [ 39, 40].
In the granulation tissue of burn wounds, expression of groα /MGSA and CXCR2 (the receptor for MGSA) was associated with fibroblasts, smooth muscle cells/myofibroblasts and a subpopulation of macrophages [ 7 ] . Groα/MGSA and IL-8 have also been shown to enhance re-epithelialization of human skin grafts in chimeric mice [ 29 38 ] . It has also been found that several CXC chemokines can modulate angiogenesis [ 39 ] , a process that is critical for proper healing.
We showed previously that cCAF is highly expressed in the granulation tissue of wounds [ 6 36 ] , that this chemokine and several of its human homologues stimulate differentiation of fibroblasts into myofibroblasts both in culture and in vivo, and that the latter effect can be achieved very effectively by the N-terminal 15aas of the protein [ 4 37 ] . In addition to cCAF, other CXC chemokines have been associated with wound healing events.
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