Words similar to ctls

Example sentences for: ctls

How can you use “ctls” in a sentence? Here are some example sentences to help you improve your vocabulary:

Furthermore, before Boon and colleagues cloned the first antigen recognized by tumor-reactive CTLs in 1991 [2], it was not clear which antigens were recognized by tumor-reactive CTLs in humans; so, it was not possible to rationally design cancer vaccines.
However, not all peptides and MHC alleles work well together to stimulate CTLs.
Some heteroclitic tumor antigen peptides that showed highly improved antigenicity and immunogenicity in preclinical studies, and which also cross-reacted well with CTLs generated against the parental sequence, were tested in clinical trials.
The authors propose that the cause for the decreased affinity of vaccine-elicited CTLs could be the high antigen density of these synthetic peptides on antigen-presenting cells.
CTLs specifically recognize and lyse targets through the interaction of T cell receptors (TCRs) on the surface of the T lymphocyte with protein fragments (peptides) presented on the surface of target cells, in association with major histocompatibility complex (MHC) class I molecules.