Example sentences for: ctl

How can you use “ctl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • One mechanism by which tumors evade immune destruction is through cytokine production or induction [ 1 ] . Prostaglandin E-2 (PGE-2), constitutively produced by many NSCLC has been identified as one factor that has direct immunosuppressive properties and is known to induce IL10 in mononuclear cells [ 2 3 4 5 6 7 ] . IL10 is a dominant immunosuppressive cytokine found in the NSCLC environment known to directly affect T cell-mediated immunity [ 2 3 4 5 6 7 8 9 10 11 12 ] . Both PGE-2 and IL10 have been shown to suppress antigen presentation, to suppress cytotoxic T cell (CTL) responses, and to inhibit cytokine production by T cells and antigen presenting cells, perhaps most importantly IL12, that plays a central role in initiation and potentiation of cellular immune responses [ 2 3 4 5 6 7 ] , [ 11 12 13 14 15 16 17 18 19 ] . We asked whether PGE-2 levels and/or IL10 levels were elevated in plasma of NSCLC patients, whether monocytes from NSCLC patients produce more IL10 than normals, and whether there was correlation within our findings.

  • CTL clones were selected directly from patient PBMC samples without enrichment in culture to closely reflect the composition of the antigen-specific T cell response in vivo at the time of isolation.

  • Comparing the pre-intervention and intervention periods, the TM group exhibited a mean total reduction of 6.4 absentee class periods compared to an increase of 4.8 in the CTL group ( F 1,33 = 4.2, p < .05, see Table 2for means).

  • There is a relative increase in the memory cell repertoire [ 17 18 19 20 ] , and an increase in absolute counts in the CD8 +CD28 -populations in both aged [ 22 ] and HIV +donors [ 22 23 24 25 ] . The CD8 +CD28 -T cell in the HIV +state appears to be the major cytotoxic T cell (CTL) [ 26 ] , but curiously, has shortened telemer lengths as well [ 27 ] .

  • As depicted in Table 2, the TM group exhibited a mean total reduction of 0.1 rule infractions over the four months of intervention compared to an increase of 0.3 infractions in the CTL group ( F 1,38 = 5.4, p < .03).


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