Words similar to ctl
Example sentences for: ctl
How can you use “ctl” in a sentence? Here are some example sentences to help you improve your vocabulary:
One mechanism by which tumors evade immune destruction is through cytokine production or induction [ 1 ] . Prostaglandin E-2 (PGE-2), constitutively produced by many NSCLC has been identified as one factor that has direct immunosuppressive properties and is known to induce IL10 in mononuclear cells [ 2 3 4 5 6 7 ] . IL10 is a dominant immunosuppressive cytokine found in the NSCLC environment known to directly affect T cell-mediated immunity [ 2 3 4 5 6 7 8 9 10 11 12 ] . Both PGE-2 and IL10 have been shown to suppress antigen presentation, to suppress cytotoxic T cell (CTL) responses, and to inhibit cytokine production by T cells and antigen presenting cells, perhaps most importantly IL12, that plays a central role in initiation and potentiation of cellular immune responses [ 2 3 4 5 6 7 ] , [ 11 12 13 14 15 16 17 18 19 ] . We asked whether PGE-2 levels and/or IL10 levels were elevated in plasma of NSCLC patients, whether monocytes from NSCLC patients produce more IL10 than normals, and whether there was correlation within our findings.
CTL) by 2 (time: pre- vs. intervention period) repeated measures ANOVAs.
A large number of clonal CTL lines (more than 200) were generated by FACS of individual G209–2M- and M26-tetramer-positive cells directly from PBMC samples (Table 2).
Descriptive characteristics of the TM and CTL groups are presented in Table 1. There were no significant main (i.e.
Clones confirmed to be tetramer-positive were expanded in T-25 flasks containing irradiated JY cells and fresh PBMCs in 25 ml of CTL medium containing PHA.
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