Words similar to ctla-

Example sentences for: ctla-

How can you use “ctla-” in a sentence? Here are some example sentences to help you improve your vocabulary:

Recently, Riley et al [ 43 ] and Diehn et al [ 44 ] described genes regulated by the TCR and the costimulatory receptors CD28, ICOS and CTLA-4, over a time course of 1-48 hours.
CTLA-4 may transduce an activating signal to CD4 +CD25 +regulatory T cells [ 2 ] . Although we did not detect any significant decrease in numbers of the CD4 +CD25 +regulatory T cells between proteoglycan-immunized BALB/c and C57BL/6 mice, this might be due to reduced expression of CTLA-4 in the CD4 +CD25 +regulatory T cells from proteoglycan-immunized BALB/c mice.
For analysis of intracellular CTLA-4, spleen cells were first stained with the above fluorescence-labeled antibodies, fixed and rendered permeable, and stained with R-phycoerythrin (PE)-labeled anti-CTLA-4 using a Cytofix/Cytoperm kit (BD PharMingen).
This finding excludes the possibility that reduced expression of CTLA-4 in the CD4 +CD25 +regulatory T cells from BALB/c mice with PGIA may mediate the induction of the disease.
These include using various adjuvants, such as incomplete Freund's adjuvant and immunomodulatory agents, such as IL-12 [4], GM-CSF [5], anti-CTLA-4 Abs [35], or heat shock proteins [36].