Words similar to coa
Example sentences for: coa
How can you use “coa” in a sentence? Here are some example sentences to help you improve your vocabulary:
1999) had shown that this is not loaded directly onto the PKS, as had been assumed, but is derived by loss of carbon dioxide from a molecule of malonyl-CoA previously loaded onto the enzyme.
Acyl-Coenzyme A dehydrogenase catalyzes the first step in mitochondrial β-oxidation, converting acyl-CoA to 2-trans-enoyl CoA.
The aromatic ring is highly stable, and CoA thioesterification can provide chemical activation, allowing cleavage of the aromatic ring, as exemplified by catabolism of benzoate, 4-hydroxybenzoate, and anthranilate [ 32].
These same conclusions regarding energy expenditure were reached in experiments assessing enzymatic activities, and transcriptional changes in rat liver using Northern blots, where fish oil feeding: increased palmitoyl CoA mitochondrial and peroxisomal oxidation rate; increased Cpt1, Cpt2, Δ 3, Δ 2-enoyl CoA isomerase, and Ech1 expression and activity; and decreased expression and activity of FA synthase, malic enzyme, glucose 6-phosphate dehydrogenase, and pyruvate kinase, compared to palm and/or safflower oil feeding [ 93 ] . Likewise, in rat white retroperitoneal adipose tissue, fish oil feeding also decreased Fasn expression [ 94 ] . Intriguingly, the hormone leptin, which also acts through SREBP-1 and PPARα, affected many transcripts similarly to LC-PUFA ( e.g. , leptin decreased Gpam and Apoa4 transcripts; and up regulated Ech1, mitochondrial Hmgcs2, and Cyp4a14 transcripts [ 95 ] .
Cpt1 transfers acyl residues from CoA to carnitine in the intermembrane space of the inner mitochondrial membrane, and has a regulatory role in controlling hepatic β-oxidation [ 50 ] . Cpt2 transfers carnitinoyl residues to CoA in the mitochondrial matrix for β-oxidation.
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