Example sentences for: coa

How can you use “coa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • If the chain-extender unit, instead of being malonyl-CoA, is methylmalonyl-CoA, which has four carbon atoms, the linear carbon chain is still extended by two carbons, and the ‘extra’ carbon forms a methyl side branch.

  • Furthermore, the essential glycolytic gene products ( pgk, gapAC ) were required for the synthesis of oxaloacetate, succinyl-CoA, α-ketoglutarate, pyruvate, phosphoenolpyruvate (PEP), and 3-phosphoglycerate within all conditions, and were unable to synthesize all biosynthetic precursors under anaerobic growth conditions.

  • The citramalate pathway for conversion of pyruvate to 2-ketobutyrate involves a carbon-chain elongation mechanism that uses an initial step of condensation with acetyl-CoA, followed by rearrangement, oxidation and elimination of a carbon to produce a keto acid differing from the original substrate by the presence of an additional carbon.

  • Acyl-Coenzyme A dehydrogenase catalyzes the first step in mitochondrial β-oxidation, converting acyl-CoA to 2-trans-enoyl CoA.

  • Thus, LC-PUFA can activate PPARα/RXRα, leading to displacement of HNF4α from PPRE; or be converted to CoA derivatives, which in turn can suppress HNF4α transcriptional activity.


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