Example sentences for: cationic

How can you use “cationic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, sensitivity to the antibacterial lipopeptide polymyxin B is affected by the PmrA-PmrB regulon, which mediates substitution of 4-aminoarabinose on the 4´ phosphate of lipid A [ 52 53 ] . By reducing the negative charge of lipid A, this modification decreases its electrostatic interaction with cationic peptides.

  • The F-actin-binding activity of moesin is regulated by both phosphorylation and polyphosphoinositides (PIPs) 1. Interestingly, PIPs could be substituted for by a cationic detergent, dodecyltrimethylammonium chloride (DOTMAC) in vitro [ 19].

  • Tetraethylammonium is known as a pore-occluding blocker of voltage-gated potassium channels [ 1 ] , but it also blocks other cationic channels such as calcium-dependent K +channels [ 2 3 ] and the nicotinic acetylcholine receptor [ 4 ] . TEA at 0.1 to 10 mM also inhibits osmotic water flux through human AQP1 channels expressed in Xenopus oocytes, decreasing the net swelling rate in hypotonic saline by 30-40% as compared to AQP1-expressing oocytes not treated with TEA [ 5 ] . This blocking effect on osmotic water flux was demonstrated to involve AQP1 channels specifically by using site-directed mutagenesis (tyrosine 186 to phenylalanine) to generate a Y186F AQP1 channel that is insensitive to block by TEA, but retains sensitivity to block by mercury.

  • [ 3], but the cationic detergent DOTMAC was not included.

  • Another significant factor may be the difference in charge between the buffer salts; phosphate is anionic whereas Tris is cationic and zwitterionic.


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