Example sentences for: cationic

How can you use “cationic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The magnitude of change in t PTEF / t E was significantly correlated with the concentration of serum eosinophilic cationic protein (an inflammatory marker) [ 7].

  • For example, PEI has a very high cationic charge density, making it useful for binding anionic DNA within the physiological pH range [ 4] and forcing the DNA to form condensates small enough to be effectively endocytosed [ 5], which is the primary mode of the PEI/DNA complex into the cell [ 1, 6, 7].

  • Resistance to polymyxin B is also imparted by the absence or masking of critical binding sites required for polycation-mediated permeabilization of the outer membrane [ 54 ] . Thus, attachment of polymyxin B to Yersinia enterocolitica is reduced by steric hindrance generated by the size and/or branched shape of the outer core region of its LPS macromolecule [ 55 ] . Additionally, resistance to cationic peptides can be due to cytoplasmic clearance of the antimicrobial peptide by an efflux pump; e.g., Yersinia resistance to polymyxin B caused by the RosA/RosB efflux pump/potassium antiporter [ 56 ] and Neisseria gonorrhoeae resistance to protegrin PG-1 via an energy-dependent efflux system termed mtr [ 57 ] .

  • Tetraethylammonium is known as a pore-occluding blocker of voltage-gated potassium channels [ 1 ] , but it also blocks other cationic channels such as calcium-dependent K +channels [ 2 3 ] and the nicotinic acetylcholine receptor [ 4 ] . TEA at 0.1 to 10 mM also inhibits osmotic water flux through human AQP1 channels expressed in Xenopus oocytes, decreasing the net swelling rate in hypotonic saline by 30-40% as compared to AQP1-expressing oocytes not treated with TEA [ 5 ] . This blocking effect on osmotic water flux was demonstrated to involve AQP1 channels specifically by using site-directed mutagenesis (tyrosine 186 to phenylalanine) to generate a Y186F AQP1 channel that is insensitive to block by TEA, but retains sensitivity to block by mercury.

  • Synthetic vectors include cationic polymers such as polyethyleneimine (PEI) and polylysine, as well as cationic lipids such as Lipofectamine [ 2] and negatively charged liposomes [ 3].


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