Example sentences for: cation-π

How can you use “cation-π” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This orientation of an amino group interacting with an aromatic amino acid in a cation-π interaction has been shown for the nicotinic acetylcholine receptor and has been hypothesized for many LGIC receptors [ 28 29 30 26 ] . This conclusion is based on both the magnitude of the change observed on the wild type receptor for removal of the amino group (400 fold) compared to the effect of the Y142A mutation on lerisetron binding (160 fold) and the lack of any major change in K i for analog 2 as a result of this mutation.

  • al . have suggested that W183 may be involved in a cation-π interaction with the amino group of 5-HT and m CPBG [ 26 ] . If W183 and Y142 are located near each other but on opposite faces of the binding site in the 5-HT 3 R, then they could potentially act in concert to help stabilize a conformation of the receptor leading to channel opening.

  • Y142 is shown interacting with the distal piperazine nitrogen possibly through a cation-π interaction.


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