Example sentences for: cations

How can you use “cations” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Some of the RNA polymerases function as single-subunit proteins, whereas others form large complexes that consist of multiple, distinct subunits; however, in all known cases, the basic catalytic activity maps to a single polypeptide containing a characteristic metal-chelating active site [ 5 6 7 ] . Typically, active sites of polymerases contain acidic or polar residues, which coordinate divalent metal cations, most often Mg 2+.

  • The metal cations direct a 5' nucleoside triphosphate to form a phosphoester bond with the 3' hydroxyl of the preceding nucleotide (the 3'-terminal nucleotide of a growing polynucleotide chain), with the elimination of pyrophosphate [ 6 ] .

  • Closely spaced acidic residues that coordinate divalent cations are characteristic of the active sites of most nucleic acid polymerases, in spite of the fact that they belong to several unrelated structural folds [ 9 13 14 17 28 29 59 ] . Given that the DbDGD motif is the only set of closely spaced acidic residues shared by the RDRPs and the YRHs, it is likely to form part of the nucleotidyltransferase active site of these enzymes.

  • Numerous factors determine the effect of mismatches, including: the length of the oligonucleotide, the nature and position of the mismatches, the temperature of hybridization, the presence of co-solvents and the concentrations of oligonucleotides, as well as monovalent and divalent cations [ 6 ] .

  • An intriguing question remains regarding the location of the permeation pathway for cations in AQP1 channels.


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