Words similar to catalytically

Example sentences for: catalytically

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In the study of Takata and Kurosaki [ 11], Btk was rendered catalytically inactive by an R525Q mutation.
The middle histidine of the histidine triad (His96 in human Fhit), which is critical for hydrolysis of ApppA by Fhit [ 14 16 ] , is not necessary for tumor suppression [ 17 18 ] . Nonetheless, wild-type and His96Asn forms of Fhit are saturated by ApppA in the low micromolar range and form stable complexes with non-hydrolyzable ApppA in which two ApppA analogs are bound per Fhit dimer and all phosphates cluster on one surface of the protein [ 16 ] . These observations suggested that Fhit-substrate complexes may be the active, signaling form of Fhit and that the function of the catalytically essential histidine may be to terminate the lifetime of signaling complexes [ 16 ] .
1B), thus substantiating our contention that the p66 WTsubunit of the p66 WT/p51 INSmutant tends to self-dimerize and form the catalytically active p66 homodimer.
Finally, catalytically inactive versions of the CYTH domain are found fused to the nucleotide kinase domain in uridine kinase homologs and may serve as an allosteric nucleotide-binding site in these enzymes (Fig.
The RNase H activity seen in case of the p66 WT/p51 INSmutant was not surprising since the p66 WTsubunit of the p66 WT/p51 INSmutant tends to self-dimerize and form the catalytically active p66 homodimer.