Example sentences for: catalytically

How can you use “catalytically” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The middle histidine of the histidine triad (His96 in human Fhit), which is critical for hydrolysis of ApppA by Fhit [ 14 16 ] , is not necessary for tumor suppression [ 17 18 ] . Nonetheless, wild-type and His96Asn forms of Fhit are saturated by ApppA in the low micromolar range and form stable complexes with non-hydrolyzable ApppA in which two ApppA analogs are bound per Fhit dimer and all phosphates cluster on one surface of the protein [ 16 ] . These observations suggested that Fhit-substrate complexes may be the active, signaling form of Fhit and that the function of the catalytically essential histidine may be to terminate the lifetime of signaling complexes [ 16 ] .

  • The figure also introduces two derivatives of the 'molecule' icon: a 'dimer' icon (adapted from Kohn [ 6]) to represent dimers such as cyclin D1-Cdk4 and a 'biomolecule' icon as a shorthand to represent catalytically active molecules with both 'concentration' and 'activity' properties (for example the kinases in the mitogen-to-ERK and -Akt kinase cascades).

  • Finally, catalytically inactive versions of the CYTH domain are found fused to the nucleotide kinase domain in uridine kinase homologs and may serve as an allosteric nucleotide-binding site in these enzymes (Fig.

  • In the study of Takata and Kurosaki [ 11], Btk was rendered catalytically inactive by an R525Q mutation.

  • 1B), thus substantiating our contention that the p66 WTsubunit of the p66 WT/p51 INSmutant tends to self-dimerize and form the catalytically active p66 homodimer.


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