Words similar to catalytic
Example sentences for: catalytic
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Mammalian protein phosphatase 5 (PP5) and its homolog protein phosphatase T1 (Ppt1p) from the yeast Saccharomyces cerevisiae contain a catalytic domain structurally related to the catalytic subunits of PP1, PP2A and PP2B, and an N-terminal domain consisting of multiple tetratricopeptide repeats (TPRs) not found in other members of this family of phosphatases [ 1 2 3 ] . Homologs have also been identified in Xenopus laevis [ 4 ] , Neurospora crassa [ 5 ] , Drosophila melanogaster [ 6 ] , Trypanosoma brucei [ 7 ] , Plasmodium falciparum [ 8 9 ] , and cauliflower [ 10 ] , and homologs for Caenorhabditis elegans, Schizosaccharomyces pombe and Arabidopsis thaliana are predicted (accession number CAB60937, CAA17690 and AAD21727, respectively).
Yersinia pestis and Borrelia burgdorferi and the archaea, its antecedents or catalytic mechanism have not been understood.
The presence of completely different conserved residues and the asymmetric head to tail arrangement of the monomers in the pair suggest that the ancestral DPBB dimer was not specialized, had no catalytic activity, and merely bound RNA.
However, the p66 INS/p66 INSand p66 INS/p51 INSmutants displayed nearly 6,000-fold and 400-fold reduction in catalytic efficiency (k cat /Km) compared to their wild type counterparts, respectively, on this template primer.
One of these corresponds to the catalytic, metal-coordinating domain, containing the DbDGD motif, in the β' subunit (residues: 626-750 of pdb id:1iw7 chain D), whereas the other one corresponds to the conserved core domain of the β subunit (residues:673-994 of pdb id: 1iw7 chain C).
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