Words similar to catalytic

Example sentences for: catalytic

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The second mammalian RNase III orthologue also exhibits a single C-terminal dsRBM and tandem catalytic domains, but is otherwise structurally distinct from Dicer as it lacks the helicase and PAZ domains (Figure 1) [ 18 19 ] . Preliminary evidence indicates that this RNase III orthologue participates in rRNA maturation.
The replicative polymerase of herpes simplex virus (HSV) is comprised of catalytic (Pol) and processivity subunits (UL42) [ 9 11 ] . HSV Pol is responsible, in concert with other viral proteins, for regulating the fidelity of DNA replication by selecting the correct nucleotides for incorporation and by proofreading or editing mispaired nucleotides [ 20 ] . The Pol subunit contains intrinsic 3'-5' exonuclease activity [ 14 15 16 ] and the N-terminal region of the polypeptide encoding this function is highly conserved in other polymerases, containing three segments referred to as Exo motifs [ 3 26 ] .
During the Topo I catalytic process, a transient covalent linkage, termed the 'cleavable complex', is formed between the enzyme and DNA strand nicks.
To guard against this scenario, control over the amount of PP1 catalytic subunit present via an autoregulatory mechanism would be beneficial.
However, the atomic structures and catalytic mechanisms of the fungal and mammalian RNA triphosphatases are completely different [ 2 3 ] . Thus, it has been suggested that RNA triphosphatase is a promising target for antifungal drug discovery [ 2 ] .