Example sentences for: catalyze

How can you use “catalyze” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Organic phosphate compounds are the central metabolites of all biological systems [ 1 2 ] . Some are the basic building blocks of nucleic acids, some like ATP and GTP, are additionally, cellular energy stores, others like cAMP or cGMP are messengers in signal transduction, and, yet others, such as FAD, NAD, thiamine phosphates and pyridoxal phosphate are cofactors for a range of enzymes [ 1 2 ] . Protein domains belonging to a relatively small set of structural folds are known to bind or catalyze reactions that utilize these organic phosphate compounds (see SCOP database: http://scop.mrc-lmb.cam.ac.uk/scop/) [ 3 4 ] . Several of these folds trace back to some of the earliest phases of the evolution of the protein world, and participate in a wide range of disparate biological functions in extant proteins [ 4 5 ] . Some folds, such as the P-loop fold, the Rossmann fold and the Hsp70-like fold, have been well studied, and comprise mainly of dedicated nucleotide binding or hydrolyzing proteins [ 6 7 8 9 ] . Others, such as the palm-domain, which is found in adenylyl cyclases and various nucleic acid polymerases, belong to more generalized protein folds that contain representatives with diverse biochemical activities [ 4 10 11 ] . Current availability of extensive genome sequence data, allows one to identify less numerous, nevertheless biological important organic phosphate-binding domains that may have previous eluded detection.

  • In plants, enzymes of this family catalyze the formation of the plant hormone ethylene by oxidative desaturation of 1-aminocyclopropane-1-carboxylate, and catalyze the hydroxylation and desaturation steps in the synthesis of other plant hormones, pigments and metabolites such as gibberellins, anthocyanidins and flavones [ 1, 6, 7].

  • Alliances between nongovernmental organizations and drug companies could catalyze research into the diseases that plague poor nations.

  • Assigning function by sequence homology alone is subject to a number of caveats, including the occurrence of structurally homologous enzymes that catalyze different reactions [ 3] and the propagation of error through successive rounds of sequence annotation [ 4].

  • Several enzymes, including isoforms of alcohol dehydrogenase, ALDH, and cytochrome P450 (CYP), recently have been shown to be involved in the formation of retinoic acid from retinol and retinal [ 7 8 ] . The purification, cloning, and characterization of several ALDH enzymes which efficiently catalyze the oxidation of retinal (Figure 1A) has suggested that regulation of retinoic acid formation could be a key physiologic role for these enzymes.


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