Words similar to carcinogenicity
Example sentences for: carcinogenicity
How can you use “carcinogenicity” in a sentence? Here are some example sentences to help you improve your vocabulary:
Possible side effects of the drug candidates were assessed by testing each candidate and its predicted metabolites against carcinogenicity and mutagenicity databases [ 35 ] , [ 36 ] .
Molecular methods, such as the evaluation of hormone receptors in breast carcinoma, have been effectively employed to further characterize tumors [ 1 ] . Nucleic acid array-based technologies extend molecular characterization by providing a biochemical snapshot, or profile, of cellular activity that encompasses thousands of gene products [ 2 ] . Potential applications beyond diagnosis and prognosis are diverse, and include treatment response stratification of patients in clinical trials, assessment of relevance to human safety of drug-associated tumors in animal carcinogenicity studies, and the development of more pertinent animal xenograft models of cancer therapy.
As an additional validation, each model was tested with a large group of structurally diverse molecules, which were taken from the FDA rodent carcinogenicity database [ 35 ] . Results (Table 2) demonstrate good specificity of the models.