Words similar to carcinogenic
Example sentences for: carcinogenic
How can you use “carcinogenic” in a sentence? Here are some example sentences to help you improve your vocabulary:
The evidence that adolescent diet may affect the risk of breast cancer derives from several lines of evidence [ 1 ] . Rates of breast cancer among Asian immigrants to the United States do not approach those of US white women until the second or third generation, suggesting that exposures during childhood and adolescence are important in establishing a higher risk of breast cancer [ 2 3 ] . Norwegian women who were adolescents during World War II, when average caloric intake decreased by 22%, have a reduced incidence of breast cancer, suggesting that energy restriction might affect risk [ 4 ] . Similarly, in animal models, energy restriction in the peripubertal period inhibits mammary tissue proliferation and reduces the subsequent risk of mammary tumors [ 5 6 ] . Exposure of rats to carcinogens before first pregnancy increases the incidence of mammary tumors compared with exposure after first pregnancy [ 7 ] . After differentiation of the mammary gland at the time of first full-term pregnancy of the rat, the rate of cell division decreases and length of the cell cycle increases, allowing more time for DNA repair [ 8 ] . This biologic phenomenon might explain the apparent vulnerability of the adolescent breast tissue to carcinogenic exposures.
A causal association between squamous cell carcinoma arising in the head and neck region (HNSCC) and exposure to tobacco and alcohol is well established [ 1 2 3 ] . However, 10-15% HNSCC occur in patients without any antecedent history of tobacco or alcohol exposure [ 4 5 ] . Several studies have suggested that these patients have a divergent clinical course compared to patients with tobacco associated HNSCC, which may be a reflection of differences in the genetic composition [ 4 5 6 ] . Empiric evidence suggesting that non-smokers may respond differently to carcinogenic insults is offered in a report by Schantz et al.
Although less frequent, 1p gains are also common to many tobacco-associated malignancies [ 11 13 14 15 16 ] . Work by Racz and colleagues suggest that PAX7 and ENO1 may be candidate oncogenes in this region [ 21 ] . PAX7 is part of a family of transcription factors known to be carcinogenic.
Since these syndromes may have enormous relevance to our understanding of the carcinogenic process, they were collected as a separate listing.
The carcinogenic risk cited in the literature on aristolochic acid [ 61 ] needs to be evaluated versus its potential benefit as an emergency medicine for snake and scorpion bites.
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