Words similar to carboxylate

Example sentences for: carboxylate

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Variations at residues alpha4 Thr183 and beta2 Ala135 generate different shapes of the binding pocket (Figure 4- Top), but preserve the electrostatic potential of the system: all non-conserved residues at position 183 are hydrophobic, and hydroxyl of Thr154 and Ser154 are superimposed, pointing away from the ligand, towards the carboxylate of Asp122.
All sequenced subclass Ba and Bb metallo-β-lactamases (except VIM-1) have a lysine residue at position 224 [ 41 ] , and all computational models for substrate binding to the metallo-β-lactamases assume that the invariant carboxylate on substrates forms an electrostatic interaction with this lysine.
These include O -acetylserine sulfhydrylase, threonine deaminase, threonine synthase, cystathionine β-synthase, 1-aminocyclopropane-1-carboxylate deaminase, L-serine dehydratase, and D-serine dehydratase.
In plants, enzymes of this family catalyze the formation of the plant hormone ethylene by oxidative desaturation of 1-aminocyclopropane-1-carboxylate, and catalyze the hydroxylation and desaturation steps in the synthesis of other plant hormones, pigments and metabolites such as gibberellins, anthocyanidins and flavones [ 1, 6, 7].
The nucleophilicity of the thiol in γ-Glu-Cys should be diminished by the proximity of the negatively charged carboxylate.