Words similar to carboxylate

Example sentences for: carboxylate

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The ATP-grasp superfamily [ 41] includes at least 15 families of enzymes that catalyze formation of a bond between a carboxylate group of one substrate and an amino, imino or thiol group of a second substrate.
The conserved basic residue interacts with the carboxylate group of the acidic substrate, while the bulky or aromatic residue located carboxy-terminal to the basic one forms the base of the cleft that holds this substrate molecule (Figure 2).
The same result was obtained when p66 INSwas dimerized with p51 having Asp→Ala mutation at amino acid position 186 (one of the catalytically crucial carboxylate triad) but having an intact β7-β8 loop.
Among the two carboxylate polymers (Carbomer 974P and CAP), only soluble CAP (at neutral pH) was able to elicit the formation of gp41 six-helix bundles in both HIV-1 IIIB and BaL and was virucidal against both of these viruses.
Variations at residues alpha4 Thr183 and beta2 Ala135 generate different shapes of the binding pocket (Figure 4- Top), but preserve the electrostatic potential of the system: all non-conserved residues at position 183 are hydrophobic, and hydroxyl of Thr154 and Ser154 are superimposed, pointing away from the ligand, towards the carboxylate of Asp122.