Words similar to carboxyl-terminal
- carbon-dating
- carbondale
- carbonizzato
- carboxy-tetramethyl-rhodamine
- carboxyethyl
- carboxyfluorescein
- carboxykinase
- carboxyl
- carboxyl-activated
- carboxyl-terminal
- carboxyl-termini
- carboxyl-terminus
- carboxylase
- carboxylases
- carboxylate
- carboxylesterase
- carboxymethyl-
- carboxymethyl-lysine
- carbón
- carcaterra
Example sentences for: carboxyl-terminal
How can you use “carboxyl-terminal” in a sentence? Here are some example sentences to help you improve your vocabulary:
Whereas the genome of Fugu rubripes is one order of magnitude shorter than the length of the human genome, the total number of genes is estimated to be approximately the same [ 8 9 ] . Because of the low homology of amino- and carboxyl-terminal sequences, we were not able to determine the complete coding sequences of the eight pufferfish TMC proteins unequivocally; nevertheless, we obtained sufficient sequence information of the central parts of the proteins bearing the transmembrane domains to classify the eight pufferfish TMCs into the three subfamilies.
AtCOP1 contains three conserved structural domains: a RING finger at the amino terminus, a coiled-coil domain in the middle, and a carboxyl-terminal WD40 repeat domain [ 9 10 ] . Each of the three conserved domains has been shown to mediate protein-protein interactions [ 11 12 13 ] . The subcellular localization of AtCOP1 is regulated by light in a tissue specific manner [ 14 15 ] . The hypocotyl cell nuclei contain high levels of COP1 in the dark and reduced levels in the light, suggesting that the nucleocytoplasmic partitioning of AtCOP1 is adjusted by a light-responsive mechanism [ 14 16 ] . The activity of AtCOP1 is at least in part regulated by its subcellular localization, as the degradation of HY5 is dependent upon the nuclear accumulation of AtCOP1 in the dark [ 4 ] . AtCOP1 was demonstrated to carry a single, bipartite nuclear localization signal located between the coiled-coil domain and the WD-40 domain (amino acid 294-314) and a cytoplasmic localization signal, which was mapped to a region partially overlapping with the RING finger and the coiled-coil domain (amino acid 67-117) [ 17 ] . Strikingly, AtCOP1 protein forms characteristic nuclear speckles when transiently expressed in onion epidermal cells or stably expressed in transgenic Arabidopsis [ 6 18 ] . The functional role of these speckles is currently unknown; however, a subnuclear localization signal consisting of 58 residues (amino acid 120-177) is required for their formation [ 19 ] .
These enzymes have a conserved domain organization that includes a highly novel protein kinase catalytic domain unrelated to conventional kinases, and a carboxyl-terminal WD repeat domain that targets these enzymes to myosin II filaments (Figure 1).
Aggrecan and versican are aggregating proteoglycans that are key constituents found in the extracellular matrix [ 41 ] . Both proteoglycans contain amino-terminal hyaluronic acid-binding regions, central core glycosaminoglycan attachment domains, and carboxyl-terminal domains containing EGF-like modules (one in aggrecan and two in versican), C-type lectin like modules and complement regulatory protein-like modules [ 49 50 ] . Fibulin-1 exhibits calcium-dependent binding to the carboxyl-terminal domain of aggrecan and versican [ 41 ] . The binding site of aggrecan to fibulin-1 maps to the type II EGF-like modules 8-9 and the carboxyl-terminal domain of fibulin-1 [ 41 ] . The binding site of versican to fibulin-1 maps to the type II EGF-like modules 2-8 of fibulin-1 [ 41 ] .
Tmc3 bears a long carboxyl-terminal tail that is unlike all other TMC proteins (Figure 1).
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