Words similar to carboxylterminal
Example sentences for: carboxylterminal
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The phosphorylation of Smad1 at the carboxylterminal SSVS motif triggers the release of Smad1 from the receptor, the formation of homo-oligomers of Smad1 and hetero-oligomers of Smad1 and Smad4, and the subsequent nuclear translocation of both Smad1 and Smad4 [ 6 9 10 ] . In the nucleus, Smad1 and Smad4 function as DNA-binding transcriptional regulators [ 9 ] . However, there is a unique feature in Smad-regulated transcription.
However, a short conserved cytoplasmic motif in the carboxylterminal region of Fzs, including DFz2, was reported to be important for the activation of Wnt/β-catenin signaling in mammalian cells, based on mutational analysis [ 20 ] .