Example sentences for: calcineurin

How can you use “calcineurin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Like calcineurin (PP2B) and PP2C, PP7 is apparently insensitive to inhibition by okadaic acid [ 20].

  • On the basis of sequence homo logy and similarity of three-dimensional structures, phosphoprotein phosphatases (PPases) have been classified into three families designated PPP, PPM, and PTP [reviewed in [ 1 2 3 ] . The PPP and PPM families are comprised of phosphoserine- and phosphothreonine-specific enzymes whereas the PTP family consists of phosphotyrosine-specific and dual-specificity enzymes [ 4 ] . The major members of the PPP family are PP1, PP2A, and PP2B (calcineurin) class of phosphatases.

  • We have also shown that recombinant NFATp purified from insect cells is a phosphoprotein that exhibits association with nuclei in vitro only after dephosphorylation by calcineurin.

  • The shift in migration of HA-NFATp was dependent on both calcineurin and calmodulin, and was not efficiently produced with other phosphatases (data not shown).

  • HA-NFATp was either treated with calcineurin and calmodulin or mock treated, and the two proteins were then mixed with the nuclei.


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