Words similar to c-kit

Example sentences for: c-kit

How can you use “c-kit” in a sentence? Here are some example sentences to help you improve your vocabulary:

Since the effect of Gleevec is mediated through inhibiting BCR-ABL tyrosine kinase, c-kit, and PDGF receptors, we are interested in the potential target for Gleevec effect in the lung cancer cells.
These results lead us to find an alternative target for Gleevec, because of the low expression level and low frequency of expression of c-kit in the lung cancer patients.
Gleevec has been shown to induce clinical, hematological and molecular remissions for CML patients [ 4 ] . It cross-reacts with two other important growth factor receptors containing tyrosine kinase domains, c-kit and PDGF receptors, that play important roles in growth and proliferation of a variety of cell types [ 5 ] . C-kit (also known as CD117) is frequently mutated in gastrointestinal stromal tumor (GIST), and the mutated c-kit shows higher tyrosine kinase activity.
Gleevec was designed to inhibit the BCR-ABL tyrosine kinase, and it cross-reacts with c-kit and PDGFR [ 5 ] . In non-small cell lung cancer, BCR-ABL expression has never been reported, and it is unlikely that BCR-ABL fusion protein plays any role in lung cancer.
We have studied the expression of c-kit (CD117) in the non-small cell lung cancer patients, and we found that approximately 13% of the tumor specimens were weakly positive for c-kit.